2 documents found, page 1 of 1
Vernonia britteniana Root Phytochemical Studies, In Vitro Cercaricidal Activity...
Valente, Maria dos Anjos; Ferreira, Pedro; Lima, Katelene; Moreira da Silva, Isabel B.; Nobre, Paula; Neto, Isabel; Pires, Mavilde; Braz, Berta SãoFunding Information: This research was funded by the Foundation for Science and Technology (FCT, Portugal) through national funds FCT/MCTES to iMed.ULisboa (UIDP/04138/2020). Publisher Copyright: © 2023 by the authors.; Vernonia britteniana Hiern. (Asteraceae) is a medicinal plant used in traditional Angolan medicine against schistosomiasis. Our study aimed to investigate the phytochemical composition and the c...
In vitro assessment of the efficacy of a macrocyclic chelator in reversing meth...
Nobre, Paula; Cabral, Maria de Fátima; Costa, Judite; Castro-Caldas, Margarida; Carvalho, Cristina; Branco, VascoPTDC/MED-FAR/31136/2017 UID/DTP/04138/2019 project REDE/1518/REM/2005 Norma Transitoria-DL57/2016/CP1376/CT002; Methylmercury (MeHg) is a highly neurotoxic compound to which human populations are exposed via fish consumption. Once in cells, MeHg actively binds thiols and selenols, interfering with the activity of redox enzymes such as thioredoxin (Trx) and the selenoenzyme thioredoxin reductase (TrxR) which int...