Thymoma is a relatively rare tumour, being, nonetheless, the most frequent neoplasm of the anterior mediastinum. Radical surgery is the gold-standard in every stage, with a considerable recurrence rate in locally advanced tumours. Complete resection in recurrences occurs only in a few cases. A new therapeutic strategy has emerged: the Hyperthermic Intrathoracic Chemotherapy (HITHOC), a high concentrated dose of...
. A 83 year old woman with history of arterial hypertension, hypothyroidism, obesity, chronic renal insufficiency and incipient dementia was transferred to our hospital after complaints of chest pain. Investigation revealed a sacular ascending aortic aneurysm with the aneurysmal sac adjacent to the sternum. Due to her age, cognitive state and risk of sternal entry, she was refused for surgery. She was discharge...
Internal mammary artery (IMA) harvesting is a central part in coronary artery bypass grafting (CABG). The technique of harvesting the IMA - pedicled, skeletonized, or semi-skeletonized, may influence intra-operatory and postoperatory outcomes. We aim to review current evidence regarding the advantages and disadvantages of these techniques, and their performance in certain subsets of patients.
Introduction: The increase in the prevalence of aortic stenosis due to an aging population has led to an increasing number of surgical aortic valve replacements. Over the past 20 years, there has been a major shift in preference from mechanical to bioprosthetic valves. However, despite efforts, there is still no "ideal" bioprosthesis. It is crucial to understand the structure, biology, and function of native he...
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Introduction/Objectives: Repair of post-dissection thoraco-abdominal aortic aneurysms (PD-TAAA) is a complex challenge. Choosing the correct approach to manage these aneurysms is not straightforward as both open and endovascular strategies are valid. Our aim was to analyze and compare the results of PD-TAAA treated by endovascular or open surgery. Methods: A seven-year (January-2013 and May-2020) single-center ...
Fluoroquinolone use has been associated with collagen disease events, raising safety concerns. We hypothesized that the use of fluoroquinolones is associated with aortic aneurysm (AA) and aortic dissection or aortic rupture (AD/AR). We performed a systematic review with meta-analysis on studies published until March 2019. Seven observational studies were included, comprising 2,851,646 participants. The studies ...
Introduction: Aortic valve stenosis (AS) is the most common valvular pathology in the elderly and surgery (AVR) remains the gold-standard. However, transcatheter aortic valve replacement (TAVI) has become an emerging alternative to surgery. In a recent survey from the European Society of Cardiology, 9,4% stated that age was the main reason to propose for TAVI. Methods: Single-center retrospective study includin...