6 documents found, page 1 of 1
Adrenoleucodistrofia Ligada ao X: Uma Causa de Insuficiência Supra-Renal Primár...
Rebelo, Sandra; Ferreira, Tiago; Nobre, Ema; Tornada, AnaA adrenoleucodistrofia ligada ao cromossoma-X é uma doença rara caracterizada por uma mutação no gene ABCD1, que resulta no aumento de ácidos gordos de cadeia muito longa (AGCML). Reportamos o caso de um homem de 23 anos com adinamia, hiperpigmentação da pele, episódios de náuseas e hipoglicemia desde os 13 anos. Admitido por mal-estar geral, vómitos, dor abdominal e cefaleia. Apresentava-se hipotenso, taquicár...
Factors for second non-diagnostic ultrasound-guided fine-needle aspiration cyto...
Cosme, Inês; Nobre, Ema; Bugalho, Maria JoãoIntroduction: Results in fine-needle aspiration cytology (FNAC) of thyroid nodules may be non-diagnostic (ND). In these cases, it is recommended to repeat the FNAC. The aim of our study was to evaluate the influence of demographic, clinical and ultrasound (US) characteristics in the recurrence of an ND result in thyroid nodule FNAC. Methods: A retrospective study of ND thyroid nodule FNAC was performed for the ...
Usefulness of a clinicopathological classification in predicting treatment-rela...
Peixe, Carolina; Alexandre, Maria Inês; Gomes, Ana Raquel; Nobre, Ema; Silva, Ana Luísa; Oliveira, Tiago; Lopez-Presa, Dolores; Faria, ClaudiaPurpose: A clinicopathological classification has been designed to predict recurrence/progression in patients with pituitary adenomas (PAs). We aimed to study its usefulness in predicting PAs that will have a challenging disease course and may require more often complex multimodal and multiple therapeutic approaches. Methods: Retrospective analysis of 129 patients with PAs operated in our institution between 20...
Different antibody-associated autoimmune diseases have distinct patterns of T f...
Ribeiro, Filipa; Romão, Vasco C.; Rosa, Sara; Jesus, Kátia; Agua-Doce, Ana; Barreira, Sofia; Martins, Patrícia; Silva, Susana; Nobre, EmaAutoantibodies are produced within germinal centers (GC), in a process regulated by interactions between B, T follicular helper (Tfh), and T follicular regulatory (Tfr) cells. The GC dysregulation in human autoimmunity has been inferred from circulating cells, albeit with conflicting results due to diverse experimental approaches. We applied a consistent approach to compare circulating Tfr and Tfh subsets in pa...
Intra-gastric ballon in the treatment of morbid obesity.
Carvalho, Ma Raquel; Jorge, Zulmira; Nobre, Ema; Dias, Teresa; Cortez-Pinto, Helena; Machado, Mariana V; Camolas, José; Neves, Sílvia; Guerra, AnabelaIntragastric balloon is a temporary treatment for weight loss with proven safety and efficacy when associated with lifestyle intervention. It is indicated in the super--obese who are candidates for bariatric surgery to lose weight and to reduce their high surgical risk. Our aim was to retrospectively evaluate the results of the patients in whom this device was inserted during a three-year period from the beginn...
A rare case of hyperandrogenism: bilateral Leydig cell tumor of the ovary.
Marcelino, M; Nobre, Ema; Conceição, J; Lopes, L; Vilar, H; França Martins, M; Carvalho, A; André, S; Horta, A; De Castro, J JácomeThe androgen-secreting tumors constitute fewer than 1% of ovarian tumors. Leydig cell tumor is one of the most common of this type of lesion and it is usually benign, small and unilateral.A 67 year old woman was referred to the Endocrine clinic due to hirsutism (score 22 Ferriman-Gallwey) and male type alopecia with 3 years of evolution and progressive worsening. Biochemically she had high levels of serum testo...