12 documents found, page 1 of 2

Hepatitis B Virus Genotypes and Subgenotypes Circulating in Infected Residents ...

Despite the availability of a vaccine against hepatitis B virus (HBV), this infection still causes public health problems, particularly in susceptible populations. In Portugal, universal free vaccination started in 1994, and most HBV infections are diagnosed in immigrants from high-prevalence countries. Our aim was to assess the pattern of HBV genotypes/subgenotypes in samples collected between 2017 and 2021 fr...

Diversity of Human T-Lymphotropic Virus Type 1 Cosmopolitan Subtype (HTLV-1a) C...

Human T-cell lymphotropic virus type 1 (HTLV-1) prevalence in Portugal is low and mainly affects immigrants from endemic areas where human immunodeficiency virus (HIV) infection represents a public health problem. Despite the majority of HTLV-1-infected individuals remains asymptomatic, severe pathologies may develop after prolonged viral persistence, namely an aggressive form of leukemia. An increased mortalit...

Looking at the Molecular Target of NS5A Inhibitors throughout a Population High...

Hepatitis C virus (HCV) is associated with liver damage and an increased progression rate to cirrhosis and hepatocellular carcinoma. In Portugal, it is prevalent in vulnerable populations such as injection drug users (IDU). HCV is characterized by a high intra-host variability, and the selecting driving forces could select variants containing resistance-associated substitutions (RAS) that reduce treatment effec...

Hepatitis C in a Mobile Low-Threshold Methadone Program

Introduction: Data on the epidemiology of hepatitis C among individuals who use drugs in low-threshold settings are lacking, although crucial to assess the burden of disease and aid in the design of treatment strategies. Objective: The aim of this study was to characterize the epidemiology and disease related to hepatitis C in a population attending a low-threshold methadone program. Materials and methods: A cr...

Assessment of Hepatitis C Virus Diversity in Addition to the Frequency of Genot...

Introduction: The identification of genotypes was essential for the prognosis and treatment of hepatitis C virus chronic patients in recent years. The aims of the study were to know the frequency of genotypes diagnosed in the last six years at the laboratory, and reveal the contribution of an in-house assay for molecular characterization of viruses.Material and Methods: The genotyping of hepatitis C virus by Li...

Subtipagem do vírus da Hepatite C por sequenciação: um contributo para o conhec...

Molecular epidemiology of HIV-1 circulating among injecting drug users in the g...

Molecular epidemiology of HIV-1 circulating among injecting drug users in the Greater Lisbon Carina Sousa1; Sandra Videira e Castro1; Elizabeth Pádua3; Ricardo Parreira1,2; Aida Esteves1,2; João Piedade1,2 1Grupo de Virologia, UEI de Microbiologia Médica; 2Unidade de Parasitologia e Microbiologia Médicas (UPMM) Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa Rua da Junqueira nº100, 1349-00...

Genotypic resistance profiles to antiretroviral drugs in HIV-1 circulating amon...

Genotypic resistance profiles to antiretroviral drugs in HIV-1 circulating among injecting drug users in the Greater Lisbon Sandra Videira e Castro1; Carina Sousa1; Elizabeth Pádua3; Aida Esteves1,2; Ricardo Parreira1,2; João Piedade1,2 1Grupo de Virologia, UEI de Microbiologia Médica; 2Unidade de Parasitologia e Microbiologia Médicas (UPMM) Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa ...

VIH/SIDA e Hepatite C: uma abordagem epidemiológica, molecular e de diagnóstico

A infeção VIH/SIDA tem como base os registos oficiais de casos notificados em Portugal. Esta infeção é de declaração obrigatória desde 2005, sendo as notificações dos novos casos diagnosticados no país enviadas ao Núcleo de Vigilância Laboratorial de Doenças Infeciosas no INSA, responsável pela posterior introdução e gestão da base de dados e avaliação e divulgação dos resultados. A partir desta fonte de inform...

Evolução de casos de transmissão VIH da mãe ao filho em Portugal