4 documents found, page 1 of 1
Exploring the factor structure of neurocognitive measures in older individuals
Santos, Nadine Correia; Costa, Patrício Soares; Amorim, Liliana; Moreira, Pedro Miguel Silva; Cunha, Pedro Guimarães; Cotter, Jorge; Sousa, NunoHere we focus on factor analysis from a best practices point of view, by investigating the factor structure of neuropsychological tests and using the results obtained to illustrate on choosing a reasonable solution. The sample (n=1051 individuals) was randomly divided into two groups: one for exploratory factor analysis (EFA) and principal component analysis (PCA), to investigate the number of factors underlyin...
Arterial stiffness and influences of the metabolic syndrome: a cross-countries ...
Scuteri, Angelo; Cunha, Pedro Guimarães; Rosei, E. Agabiti; Bekaert, Sofie; Cockcrofti, John R.; Cotter, Jorge; Cucca, Francesco; De Buyzere, Marc L.Specific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim of the present study was to investigate whether spec...
The rationale/design of the Guimarães/Vizela study : a multimodal population-ba...
Cunha, Pedro Guimarães; Cotter, Jorge; Oliveira, Pedro Nuno Ferreira Pinto; Vila, Isabel; Sousa, NunoBackground: Cardiovascular disease and dementia are growing medical and social problems in aging societies. Appropriate knowledge of cardiovascular disease and cognitive decline risk factors (RFs) are critical for global CVR health preventive intervention. Many epidemiological studies use case definition based on data collected/measured in a single visit, a fact that can overestimate prevalence rates and distan...
Decreasing arterial aging by controlling blood pressure levels and hypertension...
Scuteri, Angelo; Cunha, Pedro GuimarãesArterial aging, characterized by arterial stiffening that is clinically evaluable as aortic pulse wave velocity, is risky for CV events, disability, and loss of cognitive function. Today the only adopted strategy to decrease arterial aging/ arterial stiffness is represented by decreasing BP. Selective antihypertensive drug classes (calcium channel blockers, converting enzyme inhibitors, angiotensin type 1 recep...