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COVID-19-associated Coagulopathy Characterization using Rotational Thromboelast...

Rodrigues, Anabela; Dias Domingues, Tiago; Nobre Jesus, Gustavo; Garção, Ana; Rodrigues, Ana Rita; Jacinto Correia, Catarina; Leal Pereira, Carla

Introduction: COVID-19-associated coagulopathy includes systemic and endothelial inflammation with coagulation dysregulation related to immunothrombosis. The aim of this study was to characterize this complication of SARS-CoV-2 infection in patients with moderate to severe COVID-19. Methods: An open-label, prospective observational study conducted in patients with COVID-19 moderate to severe acute respiratory f...

Date: 2023   |   Origin: Acta Médica Portuguesa

The role of TMPRSS6 gene variants in different types of iron deficiency anaemia...

Gonçalves, Lúcia; Nobre Jesus, Gustavo; Afonso, Celina; Vieira, Albertina; Maia, Raquel; Correia, Leonor; Faustino, Paula

Objective: Iron-refractory iron-deficiency anaemia (IRIDA) is a rare autosomal-recessive disease characterized by severe hypochromic microcytic anemia, low serum iron and transferrin saturation, normal-high ferritin and inappropriate high levels of the hormone hepcidin. Patients are unresponsive to iron oral treatment and present a slow persistent response to intravenous iron injections. The disease is caused b...


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