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Need of new clinical criteria for the identification of genetic Lynch syndrome.

Sousa, Rita; Lage, Pedro; Ferreira, Sara; Claro, Isabel; Francisco, Inês; Filipe, Bruno; Albuquerque, Cristina; Suspiro, Alexandra; Rodrigues, Paula

Surveillance programs in families with Hereditary Non-Polyposis Colorectal Cancer (HNPCC), which is an autossomal dominant disease, decrease colorectal carcinoma mortality. There are multiple clinical criteria for the identification of these families, mainly: the Amsterdam Criteria (ACI), the modified Amsterdam Criteria (ACII) and the Bethesda Guidelines (BG).To correlate, in families with HNPCC, the clinical c...

Date: 2008   |   Origin: Acta Médica Portuguesa
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