3 documents found, page 1 of 1
Triplaris gardneriana seeds extract exhibits in vitro anti-inflammatory propert...
Lopes Neto, José Joaquim; Almeida, Thiago Silva de; Almeida Filho, Luiz Carlos Pereira; Rocha, Talita Magalhães; Nogara, Pablo AndreiEthnopharmacological relevance: Triplaris gardneriana Wedd. (Polygonaceae family) is a plant species from Brazilian semiarid region which is used in local traditional medicine for the treatment of inflammatory condi tions such as hemorrhoids. Aim of the study: In this study, the in vitro anti-inflammatory activity of different concentrations of ethanolic extract from T. gardneriana seeds (EETg) was performed in...
Estudos in silico aplicados a compostos orgânicos de mercúrio e selênio em sist...
Nogara, Pablo AndreiConselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES; Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul - FAPERGS; Methylmercury (MeHg) is a potent neurotoxin, which is associated with the inhibition of Glutathione Peroxidase (GPx) and Thioredoxin Reductase (TrxR) selenozymes, however, the mechanism of MeH...
Síntese de (5-trifluormetil-1H-pirazol-1-IL)(quinolin-4-IL)metanonas de interes...
Nogara, Pablo AndreiCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; A convergent synthesis of a series of 16 new polysubstituted (5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)(quinolin-4-yl)methanones, starting from isatin and alky(aryl/heteroaryl) ketones, is described. The diheteroaryl methanones were achieved at yields of up to 95% by a (3 + 2) cyclocondensation reaction involving 4-alkyl(aryl/heteroar...