55 documents found, page 1 of 6
Silk sericin/chitosan supramolecular multilayered thin films as sustainable cyt...
Rosas, Miguel; Sousa, Cristiana F. V.; Pereira, Ana; Amaral, Adérito J. R.; Pesqueira, Tamagno; Patrício, Sónia G.; Fateixa, SaraSilk sericin (SS) has been widely discarded as a waste by the silk textile industry during the degumming process to obtain fibroin. However, in the past decade, an in-depth understanding of its properties and functions turned it into a high added-value biomaterial for biomedical applications. Herein, we report the molecular design and development of sustainable supramolecular multilayered nanobiomaterials encom...
Surface-enhanced Raman scattering detection of thiram and ciprofloxacin using c...
Martins, Natércia C. T.; Fateixa, Sara; Nogueira, Helena I. S.; Trindade, TitoFast detection of contaminants of emerging concern (CECs) in water resources is of great environmental interest. Ideally, sustainable materials should be used in water quality monitoring technologies implemented for such purposes. In this regard, the application of bio-based materials aimed at the fabrication of analytical platforms has become of great importance. This research merges both endeavors by explorin...
Raman imaging studies on the stability of Paracetamol tablets under different s...
Fateixa, Sara; Mulandeza, Otílio; Nogueira, Helena I. S.; Trindade, TitoThe applicability of Raman imaging for pharmaceutics production ranges from the characterization of pharmaceutical formulations, kinetic processes in drug delivery to the rapid detection and identification of counterfeit drugs/contaminants. Acetaminophen (Paracetamol, APAP) is an analgesic and antipyretic drug and one of the most consumed medicines worldwide. On the other hand, the compound 4-aminophenol (4-AP)...
Comparison of the electrochemical response of carbon-fiber-reinforced plastic (...
Ofoegbu, Stanley Udochukwu; Ferreira, Mário Guerreiro Silva; Nogueira, Helena I. S.; Zheludkevich, MikhailNo abstract available.
Carbamazepine polymorphism: a re-visitation using Raman imaging
Fateixa, Sara; Nogueira, Helena I. S.; Trindade, TitoRaman imaging methods have appeared in the last years as a powerful approach to monitoring the quality of pharmaceutical compounds. Because polymorphism occurs in many crystalline pharmaceutical compounds, it is essential to monitor polymorphic transformations induced by different external stimulus, such as temperature changes, to which those compounds may be submitted. Raman imaging with k-means cluster analys...
Colloidal nanomaterials for water quality improvement and monitoring
Estrada, Ana C.; Daniel-da-Silva, Ana L.; Leal, Cátia; Monteiro, Cátia; Lopes, Cláudia B.; Nogueira, Helena I. S.; Lopes, Isabel; Martins, Maria J.Water is the most important resource for all kind forms of live. It is a vital resource distributed unequally across different regions of the globe, with populations already living with water scarcity, a situation that is spreading due to the impact of climate change. The reversal of this tendency and the mitigation of its disastrous consequences is a global challenge posed to Humanity, with the scientific comm...
Insightful vibrational imaging study on the hydration mechanism of carbamazepine
Fateixa, Sara; Nogueira, Helena I. S.; Paixão, José A.; Fausto, Rui; Trindade, TitoAnhydrous carbamazepine (CBZ) is an anti-convulsant drug commonly used to treat epilepsy and relieve trigeminal neuralgia. The presence of the dihydrate form in commercial CBZ tablets can change the dissolution rate of the active pharmaceutical ingredient (API), thus decreasing its activity. The hydration transformation can occur during wet granulation or storage, within a few weeks, depending on the ambient co...
Chemical strategies for dendritic magneto-plasmonic nanostructures applied to s...
Fernandes, Tiago; Nogueira, Helena I. S.; Amorim, Carlos O.; Amaral, João S.; Daniel-da-Silva, Ana L.; Trindade, TitoChemical analyses in the field using surface-enhanced Raman scattering (SERS) protocols are expected to be part of several analytical procedures applied to water quality monitoring. To date, these endeavors have been supported by developments in SERS substrate nanofabrication, instrumentation portability, and the internet of things. Here, we report distinct chemical strategies for preparing magneto-plasmonic (F...
A HNO3-responsive aqueous biphasic system for metal separation: application tow...
Schaeffer, Nicolas; Vargas, Silvia J. R.; Passos, Helena; Brandão, Paula; Nogueira, Helena I. S.; Svecova, Lenka; Papaiconomou, NicolasAn acidic aqueous biphasic system (AcABS) presenting a desired and reversible phase transition with HNO3 concentration and temperature was developed herein as an integrated platform for metal separation. The simple, economical, and fully incinerable (C,H,O,N) AcABS composed of tetrabutylammonium nitrate ([N4444][NO3])+HNO3 +H2O was characterized and presented an excellent selectivity towards CeIV against other ...
Biomimetic graphene/spongin scaffolds for improved osteoblasts bioactivity via ...
Semitela, Ângela; Carvalho, Sara; Fernandes, Cristiana; Pinto, Susana; Fateixa, Sara; Nogueira, Helena I. S.; Bdikin, Igor; Completo, AntónioBiomimetics offers excellent prospects for design a novel generation of improved biomaterials. Here the controlled integration of graphene oxide (GO) derivatives with a 3D marine spongin (MS) network is explored to nanoengineer novel smart bio-based constructs for bone tissue engineering. The results point out that 3D MS surfaces can be homogeneously coated by layer-by-layer (LbL) assembly of oppositely charged...