2 documents found, page 1 of 1
Performance of an in-house human immunodeficiency virus type 1 genotyping syste...
Alemán, Yoan; Vinken, Lore; Kourí, Vivian; Pérez, Lissette; Álvarez, Alina; Abrahantes, Yeissel; Fonseca, Carlos; Pérez, Jorge; Correa, ConsueloPMID: 25671421 WOS:000349545300039; As commercial human immunodeficiency virus type 1 drug resistance assays are expensive, they are not commonly used in resource-limited settings. Hence, a more affordable in-house procedure was set up taking into account the specific epidemiological and economic circumstances of Cuba. The performance characteristics of the in-house assay were evaluated using clinical samples w...
CRF19_cpx is an evolutionary fit HIV-1 variant exclusively associated with rapi...
Kourí, Vivian; Khouri, Ricardo; Alemán, Yoan; Vercauteren, Jurgen; Pineda-Peña, AC; Theys, Kristof; Megens, S.; Moutschen, M.; Pfeifer, NicoBACKGROUND: Clinicians reported an increasing trend of rapid progression (RP) (AIDS within 3 years of infection) in Cuba. METHODS: Recently infected patients were prospectively sampled, 52 RP at AIDS diagnosis (AIDS-RP) and 21 without AIDS in the same time frame (non-AIDS). 22 patients were sampled at AIDS diagnosis (chronic-AIDS) retrospectively assessed as > 3 years infected. Clinical, demographic, virologica...