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The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplat...
Azevedo, Maria Isabel; Pereira, Anamaria Falcão; Nogueira, Ricardo Braz; Rolim, Flávio Esmeraldo; Brito, Gerly AC; Wong, Deysi Viviana T.Background: Oxaliplatin, the third-generation platinum compound, has evolved as one of the most important therapeutic agents in colorectal cancer chemotherapy. The main limiting factor in oxaliplatin treatment is painful neuropathy that is difficult to treat. This side effect has been studied for several years, but its full mechanism is still inconclusive, and effective treatment does not exist. Data suggest th...
Date: 2014
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Origin: Oasisbr