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Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patie...

Machado,Natalia Pereira; Nogueira,Eliana; Oseki,Karen; Ebbing,Pâmela Carolina Cruz; Origassa,Clarice Silvia Taemi; Mohovic,Tatiane

ABSTRACT Objectives: Innate immunity is involved in the physiopathology of ankylosing spondylitis (AS), with the participation of Gram-negative bacteria, modulation of human leukocyte antigen (HLA) B27 and the involvement of pattern recognition receptors, such as Toll-like receptors (TLRs). The aim of this study was to investigate the clinical characteristics and frequency of TLR4 polymorphisms (Asp299Gly and T...

Date: 2016   |   Origin: Oasisbr

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