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Laboratório de Farmacologia de Venenos, Toxinas e Lectinas

Neves, Antonia Tays de Souza; Nogueira Júnior, Francisco Assis; Lima, Paloma Araújo de; Tavares, Dayana Maria de Sousa; Marinho, Francisco Davi Pinto

O Laboratório de Farmacologia de Venenos, Toxinas e Lectinas, conhecido como LAFAVET, é um grupo de pesquisa que vem se dedicando a estudos de alterações renais causados por animais peçonhentos brasileiros, seus modos de ação e possíveis tratamentos. Atuante desde o ano de 1993 e coordenado pela Professora Doutora Helena Serra Azul Monteiro é certificado pela Universidade Federal do Ceará e CNPq. A grande impor...

Date: 2022   |   Origin: Oasisbr

Pain modulated by Bothrops snake venoms: Mechanisms of nociceptive signaling an...

Cavalcante, Joeliton dos Santos [UNESP]; Nogueira Júnior, Francisco Assis; Bezerra Jorge, Roberta Jeane; Almeida, Cayo

Made available in DSpace on 2022-04-29T08:32:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-15; Snake venoms are substances mostly composed by proteins and peptides with high biological activity. Local and systemic effects culminate in clinical manifestations induced by these substances. Pain is the most uncomfortable condition, but it has not been well investigated. This review discusses Bothrops...

Date: 2022   |   Origin: Oasisbr

Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 med...

Marinho, Aline Diogo; Silveira, João Alison de Moraes; Chaves Filho, Adriano José Maia; Jorge, Antônio Rafael Coelho; Nogueira Júnior, Francisco Assis

Made available in DSpace on 2021-06-25T11:09:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-30; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); University of Cambridge; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The envenomation caused by the Bothrops pauloensis snake leads to severe loca...

Date: 2021   |   Origin: Oasisbr

Activity of glucose-6-phosphate dehydrogenase (G6PD) in newborns in a public ho...

Silva, Keylla Malba da Costa e; Oliveira, Evaldo Hipólito de; Fernandes, Suenia Soares; Lins, Sarah Pereira; Nóbrega, Raquel de Almeida

In glucose 6 phosphate dehydrogenase (G6PD) deficient erythrocytes, the decrease in the reduction of NADP in NADPH, leads to a low reducing potential that interferes with the oxidative metabolic capacity of the organism, being vulnerable to hemolysis, with oxidation of the globule membrane, which can lead to the hemolytic crisis. The manifestations of G6PD deficiency are triggered by environmental factors such ...

Date: 2020   |   Origin: Oasisbr

Avaliação dos efeitos citotóxicos e renais promovidos pelo veneno da serpente B...

Nogueira Júnior, Francisco Assis

The snakes of the genus Bothrops sp. are responsible for the highest number of ophidian accidents in Brazil, according to the Ministry of Health. Acute kidney injury (AKI) is the severe complication most associated in these types of accidentes. The Bothrops alternatus snake is a species of medical importance responsible for ophidian accidents, predominantly in Southern Brazil. Thus, it was investigated renal ch...

Date: 2017   |   Origin: Oasisbr

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