O Laboratório de Farmacologia de Venenos, Toxinas e Lectinas, conhecido como LAFAVET, é um grupo de pesquisa que vem se dedicando a estudos de alterações renais causados por animais peçonhentos brasileiros, seus modos de ação e possíveis tratamentos. Atuante desde o ano de 1993 e coordenado pela Professora Doutora Helena Serra Azul Monteiro é certificado pela Universidade Federal do Ceará e CNPq. A grande impor...
Made available in DSpace on 2022-04-29T08:32:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-15; Snake venoms are substances mostly composed by proteins and peptides with high biological activity. Local and systemic effects culminate in clinical manifestations induced by these substances. Pain is the most uncomfortable condition, but it has not been well investigated. This review discusses Bothrops...
Made available in DSpace on 2021-06-25T11:09:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-30; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); University of Cambridge; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The envenomation caused by the Bothrops pauloensis snake leads to severe loca...
In glucose 6 phosphate dehydrogenase (G6PD) deficient erythrocytes, the decrease in the reduction of NADP in NADPH, leads to a low reducing potential that interferes with the oxidative metabolic capacity of the organism, being vulnerable to hemolysis, with oxidation of the globule membrane, which can lead to the hemolytic crisis. The manifestations of G6PD deficiency are triggered by environmental factors such ...
The snakes of the genus Bothrops sp. are responsible for the highest number of ophidian accidents in Brazil, according to the Ministry of Health. Acute kidney injury (AKI) is the severe complication most associated in these types of accidentes. The Bothrops alternatus snake is a species of medical importance responsible for ophidian accidents, predominantly in Southern Brazil. Thus, it was investigated renal ch...