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Unveiling the fate of adhering bacteria to antimicrobial surfaces: expression o...

Alves, Diana; Magalhães, Andreia P.; Neubauer, Damian; Bauer, Marta; Kamysz, Wojciech; Pereira, Maria Olívia

Since most antibacterial coatings reported to fight biomaterial-associated infections (BAI) fail in completely preventing bacterial colonization, it is crucial to know the impact of that small fraction of adhered bacteria in BAI recrudescence. This study aims to understand the fate of Staphylococcus aureus able to adhere to an antimicrobial coating previously developed, in terms of potential development of bact...


Co-immobilization of Palm and DNase I for the development of an effective anti-...

Alves, D.; Magalhães, Andreia; Grzywacz, Daria; Neubauer, Damian; Kamysz, Wojciech; Pereira, Maria Olívia

Biomaterial-associated infections, in particular, catheter-associated infections (CAI) are a major problem in clinical practice due to their ability to resist antimicrobial treatment and the host immune system. This study aimed to co-immobilize the antimicrobial lipopeptide Palm and the enzyme DNase I to introduce both antimicrobial and anti-adhesive functionalities to polydimethylsiloxane (PDMS) material, usin...


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