92 documents found, page 1 of 10
Transfer learning in spirometry: CNN models for automated flow-volume curve qua...
Martins, C; Barros, H; Moreira, AProblem: Current spirometers face challenges in evaluating acceptability criteria, often requiring manual visual inspection by trained specialists. Automating this process could improve diagnostic workflows and reduce variability in test assessments. Aim: This study aimed to apply transfer learning to convolutional neural networks (CNNs) to automate the classification of spirometry flow-volume curves based on a...
The Relevance of Plant-Based Diets and Micronutrient Supplementation for Body C...
Pinheiro, C; Silva, F; Rocha, I; Martins, C; Giesteira, L; Dias, B; Lucas, A; Alexandre, AM; Ferreira, C; Viegas, B; Bracchi, I; Guimarães, J; Amaro, J"Objectives: This study aimed to compare the anthropometry and body composition of vegetarian and omnivorous adults living in Portugal, while exploring nutritional and health parameters underlying observed differences. Methods: 425 omnivorous (OMNI), lacto-ovo-vegetarian (LOV), or vegan (VEG) healthy adults were recruited. Anthropometry was measured, and bioelectrical impedance analysis was performed. Participa...
Comparative analysis of micro level indicators for evaluating the progress towa...
Matos, J; Martins, C; Simões, C. L.; Simoes, RicardoWith the transition from a linear to a more circular economic model, tools are required to monitor the effect of adopted changes, and to assist in further decision-making along time. Within this context, circularity micro-indicators have been proposed by many authors as a fairly simple tool to measure progress towards a more circular economy, at the product or company level. However, these circularity micro-ind...
Added value of lymphocyte subpopulations in the classification of Sjögren's syn...
Barcelos, F; Brás-Geraldes, C; Martins, C; Papoila, AL; Monteiro, R; Cardigos, J; Madeira, N; Alves, N; Vaz-Patto, J; Cunha-Branco, J; Borrego, LMSjögren's Syndrome (SjS) is a chronic systemic immune-mediated inflammatory disease characterized by lymphocytic infiltration and consequent lesion of exocrine glands. SjS diagnosis and classification remains a challenge, especially at SjS onset, when patients may have milder phenotypes of the disease or uncommon presentations. New biomarkers are needed for the classification of SjS, thus, we aimed to evaluate ...
Multidisciplinary Development and Initial Validation of a Clinical Knowledge Ba...
Pereira, AM; Jácome, C; Jacinto, T; Amaral, R; Pereira, M; Sá-Sousa, A; Couto, M; Vieira-Marques, P; Martinho, D; Vieira, A; Almeida, A; Martins, CMost mobile health (mHealth) decision support systems currently available for chronic obstructive respiratory diseases (CORDs) are not supported by clinical evidence or lack clinical validation. The development of the knowledge base that will feed the clinical decision support system is a crucial step that involves the collection and systematization of clinical knowledge from relevant scientific sources and its...
Hemophagocytic Lymphohistiocytosis in an Adolescent with NLRP12‐Related Autoinf...
Hormigo, I; Valente Pinto, M; Cordeiro, AI; Henriques, C; Martins, C; Parente Freixo, J; Conde, M; Gouveia, C; Farela Neves, J
Added Value of Lymphocyte Subpopulations in the Classification of Sjögren's Syn...
Barcelos, F; Brás-Geraldes, C; Martins, C; Papoila, AL; Monteiro, R; Cardigos, J; Madeira, N; Alves, N; Vaz-Patto, J; Cunha-Branco, J; Borrego, LMSjögren's Syndrome (SjS) is a chronic systemic immune-mediated inflammatory disease characterized by lymphocytic infiltration and consequent lesion of exocrine glands. SjS diagnosis and classification remains a challenge, especially at SjS onset, when patients may have milder phenotypes of the disease or uncommon presentations. New biomarkers are needed for the classification of SjS, thus, we aimed to evaluate ...
Nanomedicine approaches for treating glioblastoma
Martins, C; Pacheco, C; Faria, P; Sarmento, B
Development and validation of predictive equations for spirometry in Portuguese...
Martins, C; Severo, M; Silva, D; Barros, H; Moreira, ABackground There are no data on lung function reference values for Portuguese children, and the contribution from the Portuguese data set in the Global Lung Function Initiative (GLI) is scant. Objectives We aimed to estimate new up-to-date reference values for Portuguese children by fitting a multivariable regression model to a general population sample. Further, we intended to assess the external validity of t...
Case Report: Wide Spectrum of Manifestations of Ligase IV Deficiency: Report of...
Costa e Castro, A; Maia, R; Batalha, S; Freixo, JP; Martins, C; Neves, C; Cordeiro, AI; Neves, JFDNA ligase IV deficiency is a rare autosomal recessive disorder associated with impaired DNA repair mechanisms. Most patients with DNA repair defects present with neurologic deficits, combined immunodeficiency, bone marrow failure, and/or hematologic neoplasia. We present 3 unrelated cases of ligase IV deficiency with different clinical presentations. Patient 1 presented at the age of 5 with bone marrow failure...