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Relationship between Physicochemical and Cooking Quality Parameters with Estima...

Pereira, Cristiana L.; Sousa, Inês; Lourenço, Vanda M.; Sampaio, Pedro; Gárzon, Raquel; Rosell, Cristina M.; Brites, Carla

Funding Information: Project TRACE-RICE—Tracing rice and valorising side streams along Mediterranean blockchain, grant No. 1934, of the PRIMA Programme, supported under Horizon 2020, the European Union’s Framework Programme for Research and Innovation. Research Unit, GREEN-IT Bioresources for Sustainability Base Funding https://doi.org/10.54499/UIDB/04551/2020 and Programmatic Funding https://doi.org/10.54499/U...


Fluid extraction from the left-right organizer uncovers mechanical properties n...

Sampaio, Pedro; Pestana, Sara; Bota, Catarina; Guerrero, Adán; Telley, Ivo A.; Smith, David; Lopes, Susana Santos

Funding Information: This work was mainly supported by the Fundação para a Ciência e Tecnologia (research grant – PTDC/ BEX-BID/1411/2014). Funding Information: PS was funded by a PhD fellowship FCT: SFRH/BD/111611/2015. SP was funded by a PhD fellowship FCT: SFRH/BD/130272/2017 CB was funded by a PhD fellowship FCT: SFRH/BD/141034/2018 IAT was funded by FCT Investigator IF/00082/2013, EU FP7-PEOPLE-2013-CIG (N...


Pkd2 Affects Cilia Length and Impacts LR Flow Dynamics and Dand5

Jacinto, Raquel; Sampaio, Pedro; Roxo-Rosa, Mónica; Pestana, Sara; Lopes, Susana S.

Funding: This work was supported by the Fundação para a Ciência e a Tecnologia (FCT-ANR/BEX-BID/0153/2012 research grant). SL is funded by an FCT CEEC contract for Principal Investigator. The work was also supported by Sociedade Portuguesa de Nefrologia (research grant 2015), iNOVA4Health – UID/Multi/04462/2013 (a program financially supported by Fundação para a Ciência e Tecnologia/ Ministério da Educação e Ci...


Zebrafish motile cilia as a model for primary ciliary dyskinesia

Pinto, Andreia L.; Rasteiro, Margarida; Bota, Catarina; Pestana, Sara; Sampaio, Pedro; Hogg, Claire; Burgoyne, Thomas; Lopes, Susana S.

Funding Information: Funding: This work was a product of the Project LYSOCIL funded by the European Union Horizon 2020 research and innovation under grant agreement No 811087. It received funding from Fundação para a Ciencia e tecnologia, grant PTDC/BEX-BID/1411/2014; M.R. was funded by the fellowship PD/BD/136927/2018. P.S was funded by the fellowship SFRH/BD/111611/2015; C.B. was funded by the fellowship SFRH...


Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis

Burkhalter, Martin D.; Sridhar, Arthi; Sampaio, Pedro; Jacinto, Raquel; Burczyk, Martina S.; Donow, Cornelia; Angenendt, Max; Hempel, Maja

About 1% of all newborns are affected by congenital heart disease (CHD). Recent findings identify aberrantly functioning cilia as a possible source for CHD. Faulty cilia also prevent the development of proper left-right asymmetry and cause heterotaxy, the incorrect placement of visceral organs. Intriguingly, signaling cascades such as mTor that influence mitochondrial biogenesis also affect ciliogenesis, and ca...


Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Fox...

Tavares, Barbara; Jacinto, Raquel; Sampaio, Pedro; Pestana, Sara; Pinto, Andreia; Vaz, Andreia; Roxo-Rosa, Mónica; Gardner, Rui; Lopes, Telma

undacao para a Ciencia e a Tecnologia PTDC/BEX-BID/1411/2014 Susana Santos Lopes Fundacao para a Ciencia e a Tecnologia FCT-ANR/BEX-BID/0153/2012 Sara Pestana Fundacao para a Ciencia e a Tecnologia PTDC/SAU-OBD/103981/2008 Andreia Vaz Fundacao para a Ciencia e a Tecnologia PD/BD/52420/2013 Raquel Jacinto Fundacao para a Ciencia e a Tecnologia SFRH/BPD/77258/2011 Barbara Tavares Fundacao para a Ciencia e a Tecno...


Nova era no diagnóstico da discinesia viliar primária

Constant, Carolina; Sousa, Rodrigo; Pinto, Andreia; Nunes, JF Moura; Sampaio, Pedro; Lopes, Susana S.; Bandeira, Teresa; Pereira, Luísa

Introdução: A discinésia ciliar primária (DCP) é uma doença genética rara que determina alterações estruturais e/ou funcionais dos cílios, cujo diagnóstico foi alvo de padronização recente. O objectivo deste estudo foi descrever os resultados dum processo de diagnóstico centralizado aplicado a um grupo de crianças elegíveis. Métodos: Análise descritiva dos casos com diagnóstico de DCP efectuados num período de ...


The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms ...

Roxo-Rosa, Mónica; Jacinto, Raquel; Sampaio, Pedro; Lopes, Susana Santos

Work supported by Fundacao para a Ciencia e a Tecnologia [FCT-ANR/BEX-BID/0153/2012 research grant], including funding for M.R.-R. and P.S. S.S.L. has a FCT-Investigator contract and R.J. a PhD fellowship [PD/BD/52420/2013].; In autosomal dominant polycystic kidney disease (ADPKD), cyst inflation and continuous enlargement are associated with marked transepithelial ion and fluid secretion into the cyst lumen vi...


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