27 documents found, page 1 of 3

Bioactivity of ionic liquids based on valproate in SH-SY5Y human neuroblastoma ...

The search for alternative and effective therapies to fight cancer is one of the main goals of the pharmaceutical industry. Recently, ionic liquids (ILs) have emerged as potential therapeutic agents with antitumor properties. The goal of this study was to synthesize and evaluate the bioactivity of different ILs coupled with the active pharmaceutical ingredient (API) valproate (VPA) as an antitumor agent. The to...

Synthesis and biological evaluation of Amphotericin B formulations based on org...

Nowadays, organic salts and ionic liquids (OSILs) containing active pharmaceutical ingredients (APIs) are being explored as drug delivery systems in modern therapies (OSILs-API). In that sense, this work is focused on the development of novel OSILs-API based on amphotericin B through an innovative procedure and the evaluation of the respective biological activity against Leishmania infantum. Several ammonium, m...

Proximate composition, physicochemical and microbiological characterization of ...

The aim of this work was the study of the proximate composition and profile of fatty acids, minerals, and some microbiological aspects of four edible seaweed species (Chondrus crispus, Palmaria palmata, Porphyra sp., and Ulva sp.) available in the Portuguese market for food consumption, and produced in a national Integrated Multi-Trophic System (IMTA). Methods: Moisture, ash, and total lipids were determined gr...

Survey of biogenic amines (histamine and spermidine) in commercial seafood by e...

Synthesis and Antibacterial Activity of Ionic Liquids and Organic Salts Based o...

The preparation and characterization of ionic liquids and organic salts (OSILs) that contain anionic penicillin G [secoPen] and amoxicillin [seco-Amx] hydrolysate derivatives and their in vitro antibacterial activity against sensitive and resistant Escherichiacoli and Staphylococcusaureus strains is reported. Eleven hydrolyzed β-lactam-OSILs were obtained after precipitation in moderate-to-high yields via the n...

Wastewater matrix effect on disinfection with lp/uv and mp/uv radiation

The disinfection of the wastewater effluents is important to reduce the pathogenic microorganism impact in the environment. UV radiation is one of the technologies used for this purposed. The wastewater characteristics, such as dissolved organic compounds or the presence of suspended solids can affect the efficiency of the faecal coliform bacteria removal in the disinfection process by ultraviolet (UV) radiatio...

Photolysis, ozonation and chlorination of flame retardants in water treatment

Flame retardants (FR) are added to different materials to reduce the risk of fire. They save lives, prevent injuries and property losses, and protect the environment by helping to prevent fires. In Western Europe, the average annual growth rate for 2007–2012 for all flame retardant chemicals is expected to be just over 3% in volume terms. The benefits of flame retardants must necessarily be balanced with the ri...

Bioactivity of ionic liquids based on valproate in the human osteoclastogenesis

Ionic Liquids (ILs) are salts (with at least one organic cation), that have a melting point lower than 100º C. The interest in these compounds has been increasing as well as the number of applications where they can be used. Their first applications were on batteries and in organic synthesis and soon they started to be applied on health sciences. With this work we intend to study the biological properties of IL...

Ionic Liquids Synthesis – Methodologies

Ionic Liquids (IL) are salts with at least one organic cation. The term “Ionic Liquid” has been restricted to salts with melting point below 100° C [1]. In the recent years, (ILs) have gained popularity in science and technology. The large number of possible cation/ anion combinations allows a great variety of tunable interactions; also their unique properties and characteristics make it a promising and an attr...

Study the activity of cetylpyriridinium cmpicilin on resistant and sensitive Es...

Ionic Liquids (ILs) are organic salts with melting point below 100 ºC. Their possible combinations anion/cation render them more suitable for several biological applications. Understand the activity of cetylpyriridinium ampicillin on sensitive and resistant Escherichia coli.