2 documents found, page 1 of 1
Identification of the MYST3-CREBBP fusion gene in infants with acute myeloid le...
Andrade,Francianne Gomes; Noronha,Elda Pereira; Baseggio,Rosania Maria; Fonseca,Teresa Cristina Cardoso; Freire,Bruno Marcelo RochaABSTRACT Background: Acute myeloid leukemia presenting the MYST3-CREBBP fusion gene is a rare subgroup associated with hemophagocytosis in early infancy and monocytic differentiation. The aim of this study was to define the relevant molecular cytogenetic characteristics of a unique series of early infancy acute myeloid leukemia cases (≤24 months old), based on the presence of hemophagocytosis by blast cells at ...
Immunophenotypic characterization of acute leukemia at a public oncology refere...
Noronha,Elda Pereira; Marinho,Heliana Trindade; Thomaz,Erika Bárbara Abreu Fonseca; Silva,Cintia Assunção; Veras,Geni Lourdes RamosCONTEXT AND OBJECTIVES: The incidence of acute leukemia (AL) subtypes varies according to geographical distribution. The aim here was to determine the incidence of morphological and immunophenotypic AL subtypes in the state of Maranhão, Brazil, and to correlate the expression of aberrant phenotypes in children with acute lymphoblastic leukemia (ALL) with prognostic factors. DESIGN AND SETTING: Single prospectiv...