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Genetic diversity and signatures of selection of drug resistance in Plasmodium ...

Mendes, Cristina; Salgueiro, Patrícia; Gonzalez, Vicenta; Berzosa, Pedro; Benito, Agustin; Rosário, Virgílio E. do; Sousa, Bruno de; Cano, Jorge

In Plasmodium, the high level of genetic diversity and the interactions established by co-infecting parasite populations within the same host may be a source of selection on pathogen virulence and drug resistance. As different patterns have already been described in humans and mosquitoes, parasite diversity and population structure should be studied in both hosts to properly assess their effects on infection an...

Date: 2013   |   Origin: Estudo Geral - Universidade de Coimbra
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