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In vitro and in silico evaluation of the schistosomicidal activity of eugenol d...

Souza,Isabella Maria Monteiro de; Novaes,Romulo Dias; Gonçalves,Reggiani Vilela; Fialho,Felipe Leonardo Bley; Carvalho,Diogo Teixeira

Abstract Background Eugenol shows both antibacterial and antiparasitic activities, suggesting that it might be evaluated as an option for the treatment of praziquantel-resistant schistosome. Methods The in vitro activities of three eugenol derivatives (FB1, FB4 and FB9) on adult worms from Schistosoma mansoni were examined by fluorescence and scanning electron microscopy to analyze effects on the excretory syst...

Date: 2022   |   Origin: Oasisbr
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