6 documents found, page 1 of 1
MicroMundo@UPorto: an experimental microbiology project fostering student's ant...
Antunes, Patrícia; Novais, C.; Novais, A; Grosso, F; Ribeiro, TG; Mourao, J; Perovic, SU; Rebelo, A; Ksiezarek, M; Freitas, AR; Peixe, L.Antimicrobial resistance (AMR) is a global societal challenge requiring the contribution of professionals along with general community citizens for their containment. Portugal is one of the European countries where a lack of knowledge on the correct use of antimicrobials and AMR problematic is preeminent. Moreover, youth demotivation to pursue science careers is emerging. To address these problems an innovative...
The UriCath Study: Characterization of the Use of Indwelling Urinary Catheters ...
Almeida, P; Duque, S; Araújo, A; Vilas-Boas, A; Novais, A; Gruner, H; Gorjão Clara, JPurpose: Approximately 25% of older inpatients have an indwelling urinary catheter (IUC), 45-54% unnecessarily. This study aims to describe the prevalence, indications, and complications of IUC use in Portuguese older inpatients. Methods: Multicentric, cross-sectional, observational study conducted in Portuguese internal medicine wards (UriCath). Results: Of a total of 3135 inpatients from 39 hospitals, we incl...
Eosinophilic fasciitis: an atypical presentation of a rare disease
Cabral, C; Novais, A; Araujo, D; Mosca, A; Lages, A; Knock, AEosinophilic fasciitis, or Shulman's disease, is a rare disease of unknown etiology. It is characterized by peripheral eosinophilia, hypergammaglobulinemia, and high erythrocyte sedimentation rate. The diagnosis is confirmed by a deep biopsy of the skin. The first line of treatment is corticotherapy. We present a rare case of eosinophilic fasciitis in a 27-year-old woman with an atypical presentation with symme...
mcr-1 in Carbapenemase-Producing Klebsiella pneumoniae in Hospitalized Patients...
Mendes, AC; Novais, A; Campos, J; Rodrigues, C; Santos, C; Antunes, Patrícia; Ramos, H; Peixe, L.We describe a hospital-based outbreak caused by multidrug-resistant, Klebsiella pneumoniae carbapenemase 3-producing, mcr-1-positive K. pneumoniae sequence type 45 in Portugal. mcr-1 was located in an IncX4 plasmid. Our data highlight the urgent need for systematic surveillance of mcr-1 to support adequate therapeutic choices in the nosocomial setting.
The role of sex and sex-related hormones in cognition, mood and well-being in o...
Castanho, TC; Moreira, PS; Portugal-Nunes, C; Novais, A; Costa, PS; Palha, JA; Sousa, N; Santos, NCAlterations in hormone levels during aging impact on cognition and mood. Serum concentration levels of testosterone (TT), estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), dehydroepiandrosterone sulfate (DHEAS) and prolactin (PRL) were assessed in 120 community-dwellers (51+ years of age, males and females), in a cross-sectional approach. Performance clusters based on executive funct...
Spread of an OmpK36-modified ST15 Klebsiella pneumoniae variant during an outbr...
Novais, A; Rodrigues, C; Branquinho, R; Antunes, P; Grosso, F; Boaventura, L; Ribeiro, G; Peixe, LWe aim to characterise multiple ertapenem-resistant (ERT-R, n = 15) Enterobacteriaceae isolates identified as presumptive carbapenemase producers in a Portuguese hospital in a short period of time (March-July 2010). Antibiotic susceptibility patterns, beta-lactamases, genetic relatedness [pulsed-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST)], plasmid content and major enterobacterial pori...