2 documents found, page 1 of 1
Comprehensive assessment of environmental fungus-reactive T cells response in h...
Santos, Rita F.; Coelho, Andreia L.; Rufo, João C.; Coelho, David; Gonçalves, Melany; Gonçalves, Samuel L.; Cunha, Cristina; Carvalho, AgostinhoHypersensitivity pneumonitis (HP) is an interstitial lung disease that results in parenchymal and small airways inflammation and culminates in breathlessness, negatively impacting patient’s quality of life and survival. HP is initiated by an exaggerated immune response triggered by the inhalation of a variety of environmental antigens. The identification of the triggering antigen is a cornerstone of the diagnos...
Cytokine gene polymorphisms in Pigeon Breeder's Disease expression
Freitas, Cláudia; Lima, Bruno; Martins, Natália; Melo, Natália; Mota, Patrícia; Novais-Bastos, Hélder; Alves, Helena; Sokhatska, Oksana; Delgado, LuísBackground: Exaggerated immunological response to repeated inhalation of organic or chemical dusts may lead to Hypersensitivity Pneumonitis among sensitized individuals. Only a few exposed individuals became ill and disease expression pattern is highly variable which suggest that genetic factors may play a role. Aim: To investigate interferon (IFN)-γ, tumour necrosis factor (TNF)-α, interleukin (IL)-6, transfor...