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Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neu...

Bastard, Paul; Vazquez, Sara E.; Liu, Jamin; Laurie, Matthew T.; Wang, Chung Yu; Gervais, Adrian; Le Voyer, Tom; Bizien, Lucy; Zamecnik, Colin

Life-threatening "breakthrough" cases of critical COVID-19 are attributed to poor or waning antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting auto-Abs neutralizing type I IFNs underlie at least 15% of critical COVID-19 pneumonia cases in unvaccinated individuals; their contribution to hypoxemic breakthrough cases in vaccinated people is unknown. We studied a cohort of 48 ...


NGS mapped breakpoints in balanced chromosomal rearrangements including the fir...

Tommerup, Niels; Fonseca, Ana Carolina; Mehrjouy, Mana; Rasmussen, Malene B.; Bache, Iben; Halgren, Christina; Kroisel, Peter; Midyan, Susanna

Made available in DSpace on 2018-11-26T17:40:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-06-29; Univ Copenhagen, Dept Cellular & Mol Med, Copenhagen, Denmark; Univ Sao Paulo, Dept Genet &Biol Evolut, Sao Paulo, Brazil; Med Univ Graz, Inst Humangenet, Graz, Austria; Ctr Med Genet, Center Med Genet & Primary Hlth Care, Yerevan, Armenia; Univ Leuven, Dept Human Genet, Leuven, Belgium; Rede Sarah Hosp...

Date: 2018   |   Origin: Oasisbr

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