2 documents found, page 1 of 1
The neural basis of fatigue in multiple sclerosis: A multimodal MRI approach
Novo, AM; Batista, S; Alves, C; d'Almeida, OC; Marques, IB; Macário, C; Santana, I; Sousa, L; Castelo-Branco, M; Cunha, LBACKGROUND: Fatigue is a frequent disabling symptom in multiple sclerosis (MS), but its pathophysiology remains incompletely understood. This study aimed to explore the underlying neural basis of fatigue in patients with MS. METHODS: We enrolled 60 consecutive patients with MS and 60 healthy controls (HC) matched on age, sex, and education. Fatigue was assessed using the Portuguese version of the Modified Fatig...
Apathy in multiple sclerosis: gender matters
Novo, AM; Batista, S; Tenente, J; Nunes, C; Macário, C; Sousa, L; Gonçalves, FApathy has been recognized as a frequent symptom in multiple sclerosis (MS) but uncertainty remains about its prevalence and clinical correlates. Therefore, the objective of this work was to assess the prevalence of apathy in patients with MS and to identify clinical and demographic correlates. A case-control study with 30 patients and 30 healthy controls matched for age, gender and education was performed. Apa...