6 documents found, page 1 of 1
Lipid Nanoparticles Loaded with Iridoid Glycosides: Development and Optimizatio...
Dąbrowska, Marta; Souto, Eliana B.; Nowak, IzabelaLipid nanoparticles based on multiple emulsion (W/O/W) systems are suitable for incorporating hydrophilic active substances, including iridoid glycosides. This study involved optimization of composition of lipid nanoparticles, incorporation of active compounds (aucubin and catalpol), evaluation of stability of the resulting nanocarriers, and characterization of their lipid matrix. Based on 32 factorial design, ...
Lipid nanoparticles loaded with iridoid glycosides: development and optimizatio...
Dabrowska, Marta; Souto, Eliana B.; Nowak, IzabelaLipid nanoparticles based on multiple emulsion (W/O/W) systems are suitable for incorporating hydrophilic active substances, including iridoid glycosides. This study involved optimization of composition of lipid nanoparticles, incorporation of active compounds (aucubin and catalpol), evaluation of stability of the resulting nanocarriers, and characterization of their lipid matrix. Based on 32 factorial design, ...
Chemical and Physical Properties of Meadowfoam Seed Oil and Extra Virgin Olive ...
Zielińska, Aleksandra; Wójcicki, Krzysztof; Klensporf-Pawlik, Dorota; Dias-Ferreira, João; Lucarini, Massimo; Durazzo, Alessandra; Lucariello, GiuseppeIn food industry, vegetable oils are commonly used as functional ingredients. Cold pressed oils containing fatty acids show a variety of chemical properties, which are mainly dependent on the saturation of fatty acids. In this study, we have analyzed meadowfoam seed oil (MSO), obtained from seeds of Limnanthes alba, and extra virgin olive oil (EVO). Firstly, the fatty acids composition, denoted as Cox value, wa...
Loading, release profile and accelerated stability assessment of monoterpenes-l...
Zielinska, Aleksandra; Ferreira, Nuno R.; Feliczak-Guzik, Agnieszka; Nowak, Izabela; Souto, Eliana B.Glycerol monostearate solid lipid nanoparticles (SLN) were produced by hot high-pressure homogenization technique to load alpha-pinene, citral, geraniol or limonene. SLN were composed of 1wt.% monoterpene, 4wt.% of Imwitor® 900K as a solid lipid and 2.5wt.% of Poloxamer188 as a surfactant. Empty SLN consisted of 5wt.% of Imwitor® 900K and 2.5wt.% of Poloxamer188. The mean particles size (Z-Ave) and polydispersi...
Chemical and physical properties of meadowfoam seed oil and extra virgin olive ...
Zielinska, Aleksandra; Wójcicki, Krzysztof; Klensporf-Pawlik, Dorota; Dias-Ferreira, João; Lucarini, Massimo; Durazzo, Alessandra; Lucariello, GiuseppeIn food industry, vegetable oils are commonly used as functional ingredients. Cold pressed oils containing fatty acids show a variety of chemical properties, which are mainly dependent on the saturation of fatty acids. In this study, we have analyzed meadowfoam seed oil (MSO), obtained from seeds of Limnanthes alba, and extra virgin olive oil (EVO). Firstly, the fatty acids composition, denoted as Cox value, wa...
Development and optimization of alpha-pinene-loaded solid lipid nanoparticles (...
Zielinska, Aleksandra; Ferreira, Nuno R.; Durazzo, Alessandra; Lucarini, Massimo; Cicero, Nicola; Mamouni, Soukaina El; Silva, Amélia M.; Nowak, IzabelaThe encapsulation of bicyclic monoterpene α-pinene into solid lipid nanoparticles (SLN) is reported using experimental factorial design, followed by high-end dispersion analyzer LUMiSizer®. This equipment allows the characterization of the α-pinene-loaded SLN instability phenomena (e.g., sedimentation, flotation or coagulation), as well as the determination of the velocity distribution in the centrifugal field ...