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Bioavailability of Different formulations of metformin hydrochloride in healthy...

Rodrigues Neto, Edilson Martins; Marques, Lídia Audrey Rocha Valadas; Cunha, Gilmara Holanda da; Pontes, Andrea Vieira; Lobo, Patrícia Leal Dantas

Objective: To assess the bioavailability of a formulation of metformin hydrochloride 850 mg coated tablets as test, compared to a reference product with the same dosage form, in healthy volunteers of both genders. Method: This clinical trial was designed as randomised, comparative, single-dose, open-label, two-period, two-sequence, crossover study under fasting conditions. 28 healthy volunteers (fourteen men an...

Date: 2017   |   Origin: Oasisbr



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