Objective: To assess the bioavailability of a formulation of metformin hydrochloride 850 mg coated tablets as test, compared to a reference product with the same dosage form, in healthy volunteers of both genders. Method: This clinical trial was designed as randomised, comparative, single-dose, open-label, two-period, two-sequence, crossover study under fasting conditions. 28 healthy volunteers (fourteen men an...