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Global impact of the COVID-19 pandemic on stroke volumes and cerebrovascular ev...

Nguyen, Thanh N.; Qureshi, Muhammad M.; Klein, Piers; Yamagami, Hiroshi; Mikulik, Robert; Czlonkowska, Anna; Abdalkader, Mohamad; Sedova, Petra

Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of str...


Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal

Dias, Mariana Carvalho; Reis, Ricardo Soares dos; Santos, João Vasco; Nunes, Ana Paiva; Ferreira, Patricia; Maia, Bruno; Fragata, Isabel; Reis, Joao

Introduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...


Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal

Dias, Mariana Carvalho; dos Reis, Ricardo Soares; Santos, João Vasco; Nunes, Ana Paiva; Ferreira, Patricia; Maia, Bruno; Fragata, Isabel; Reis, Joao

Introduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...

Date: 2022   |   Origin: Acta Médica Portuguesa

Global impact of COVID-19 on stroke care and IV thrombolysis

Nogueira, Raul G.; Qureshi, Muhammad M.; Abdalkader, Mohamad; Martins, Sheila Ouriques; Yamagami, Hiroshi; Qiu, Zhongming; Mansour, Ossama Yassin

Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified ...


Venous and arterial TNF-R1 predicts outcome and complications in acute subarach...

Fragata, Isabel; Bustamante, Alejandro; Penalba, Anna; Ferreira, Patrícia; Nunes, Ana Paiva; Canhão, Patrícia; Montaner, Joan

Background: There is increasing evidence for the role of inflammation in clinical outcome after subarachnoid hemorrhage (SAH). Specifically, the TNF-alfa(α) pathway seems to be relevant after SAH. Although the TNF-α main receptor, TNF-R1 is associated with aneurysm growth and rupture, its relation to prognosis is unknown. We sought to compare TNF-R1 levels in peripheral venous blood and arterial blood closer to...


Prediction of clinical outcome in subacute subarachnoid hemorrhage using diffus...

Fragata, Isabel; Alves, Marta; Papoila, Ana Luísa; Ferreira, Patrícia; Nunes, Ana Paiva; Moreira, Nuno Canto; Canhão, Patrícia

Objective: Clinical outcome in nontraumatic subarachnoid hemorrhage (SAH) is multifactorial and difficult to predict. Diffusion tensor imaging (DTI) findings are a prognostic marker in some diseases such as traumatic brain injury. The authors hypothesized that DTI parameters measured in the subacute phase of SAH can be associated with a poor clinical outcome. Methods: Diffusion tensor imaging was prospectively ...


Early Prediction of Delayed Ischemia and Functional Outcome in Acute Subarachno...

Fragata, Isabel; Alves, Marta; Papoila, Ana Luísa; Nunes, Ana Paiva; Ferreira, Patrícia; Canto-Moreira, Nuno; Canhão, Patrícia

Background and purpose: Diffusion tensor imaging (DTI) parameters are markers of cerebral lesion in some diseases. In patients with acute subarachnoid hemorrhage (SAH), we investigated whether DTI parameters measured at <72 hours might be associated with delayed cerebral ischemia (DCI) and with poor functional outcome at 3 months (modified Rankin Scale score ≥3). Methods: DTI was performed in a prospective coho...


Determinantes cardíacas do tempo de ventilação mecânica e mortalidade de doente...

Marcelino, Paulo; Germano, Nuno; Nunes, Ana Paiva; Flora, Lígia; Moleiro, Ana; Marum, Susan; Fernandes, Ana Paula

Objective: To study the influence of cardiac status on the length of mechanical ventilation, outcome and disease severity in patients admitted to an Intensive Care Unit (ICU) with exacerbation of chronic respiratory failure. Design and setting: A 30-month prospective study in a 14 bed ICU Patients and methods: Fifty nine patients were enrolled, with a mean age 74.7 +/- 9.7 years, mean length of ventilator suppo...


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