25 documents found, page 1 of 3
Lymphocyte population characterization in ovarian cancer microenvironment
Nunes, Ana Rita; Rodrigues, Tomás; Garcez, Fernanda; Ricardo, Sara; Resende, Albina Dolores; Batista-Pinto, CarlaBackground: Ovarian cancer (OC) is one of the most common gynecological cancers, with poor prognosis and high mortality [1]. A key early sign of OC is the presence of ascites [2], indicating transcoelomic metastasis and tumor spread within the peritoneal cavity [3]. The accumulation of this serous fluid facilitates migration of tumor cells, which detach from the primary tumor (PT) in multicellular aggregates, m...
Omentum picture: unraveling the enigma of the immune microenvironment in append...
Gaspar, Márcio; Rodrigues, Tomás; Nunes, Ana Rita; Garcez, Fernanda; Ricardo, Sara; Batista-Pinto, Carla; Resende, Albina DoloresBackground: Appendix obstruction triggers inflammation and exaggerated immune responses, leading the omentum, rich in Milky Spots (MS) housing immune cells, to play a vital role in peritoneal immunity. These MS collect antigens and pathogens, inducing immune responses like inflammation, immune tolerance, or fibrosis [1,2]. Their activities, including angiogenesis, stem cell differentiation, and immune resp...
Mapping pilgrims’ experience of walking the Saint James way through the lens of...
Vieira, Clara; Cunha, Jennifer; Nunes, Ana Rita; Ribeiro, Luísa Mota; Rosário, PedroThe Way of St. James is a very well-known and ancient pilgrimage, with various routes leading pilgrims to the Cathedral of Santiago de Compostela in Spain, where the remains of Saint James are buried. Over the last few years, the experience of the pilgrimage and the growing number of pilgrims walking the Saint James Way have been attracting researchers’ attention. However, studies attempting to understand the p...
Tools to persevere towards a challenging goal: lessons learned about grit along...
Nunes, Ana Rita; Moreira, Tânia; Pereira, Armanda; Zanatta, Cleia; Mota Ribeiro, Luísa; Rosário, PedroUnderstanding the factors contributing to increased perseverance and passion toward long-term goals is an ongoing research challenge. The present study explores the inner drive of individuals to achieve meaningful goals over time, despite setbacks and challenges. The scenario chosen to uncover grit processes was the Way of St. James, a long pilgrimage demanding participants’ perseverance and passion for achievi...
Social zebrafish: Danio rerio as an emerging model in social neuroendocrinology
Kareklas, Kyriacos; Teles, Magda C; Nunes, Ana Rita; F. Oliveira, RuiThe fitness benefits of social life depend on the ability of animals to affiliate with others and form groups, on dominance hierarchies within groups that determine resource distribution, and on cognitive capacities for recognition, learning and information transfer. The evolution of these phenotypes is coupled with that of neuroendocrine mechanisms, but the causal link between the two remains underexplored. Gr...
Feedforward postural adjustments before single leg droplanding in subjects with...
Sousa, Andreia; Sarmento, Leonor; Gouveia, Ana; Ribeiro, Rui; Nunes, Ana RitaChronic ankle instability (CAI) involves deregulation of feedforward postural control. But the analysis of feedforward mechanisms, including early and anticipatory postural adjustments, in tasks close to the mechanisms of injury is still missing.
Postural adjustments during single leg droplanding in subjects with chronic ank...
Sousa, Andreia; Ribeiro, Rui; Nunes, Ana Rita; Sarmento, Leonor; Gouveia, AnaChronic ankle instability (CAI) involves deregulation of postural control mechanisms and is estimated to occur in 70% of the individuals after ankle SPRAIN.
Parenting in cerebral palsy: understanding the perceived challenges and needs f...
Guimarães, Ana; Pereira, Armanda; Oliveira, André; Lopes, Sílvia; Nunes, Ana Rita; Zanatta, Cleia; Rosário, PedroCerebral palsy (CP) can be considered the most frequent childhood physical disorder. The severity and type of dysfunction depend on the brain injury. Movement and posture are the most affected areas. CP is a lifelong condition, and parenting a child with this disorder brings additional challenges (e.g., dealing with grief) and needs (e.g., information). Identifying and characterizing their challenges and needs ...
RND Efflux Systems Contribute to Resistance and Virulence of Aliarcobacter butz...
Mateus, Cristiana; Nunes, Ana Rita; Oleastro, Mónica; Domingues, Fernanda; Ferreira, SusanaAliarcobacter butzleri is an emergent enteropathogen that can be found in a range of environments. This bacterium presents a vast repertoire of efflux pumps, such as the ones belonging to the resistance nodulation cell division family, which may be associated with bacterial resistance, as well as virulence. Thus, this work aimed to evaluate the contribution of three RND efflux systems, AreABC, AreDEF and AreGHI...
Perceptual mechanisms of social affiliation in zebrafish
Nunes, Ana Rita; Carreira, Leonor; Anbalagan, Savani; Blechman, Janna; Levkowitz, Gil; Oliveira, Rui FilipeSocial living animals need to recognize the presence of conspecifics in the environment in order to engage in adaptive social interactions. Social cues can be detected through different sensory modalities, including vision. Two main visual features can convey information about the presence of conspecifics: body form and biological motion (BM). Given the role that oxytocin plays in social behavior regulation acr...