42 documents found, page 1 of 5
O Impacto das Ferramentas Digitais no Tratamento da Insónia, uma Revisão Basead...
Nunes, B; Nunes Rodrigues, R; Resende, SIntrodução: Em Portugal, a insónia tem uma prevalência estimada de 10%. O tratamento de primeira linha é a terapia cognitivo-comportamental dirigida à insónia (TCC-I), no entanto há escassez de terapeutas disponíveis. O objetivo desta revisão baseada na evidência foi averiguar a eficácia das TCC-I através de meios digitais (TCC-ID) em adultos. Métodos: Foi realizada pesquisa de metanálises, metanálises em rede ...
Antibacterial effects of novel quaternary ammonium and phosphonium salts agains...
Nunes, B; Cagide, F; Anabela Borges; Borges, F; Simoes, MAim This study investigates the mechanisms of action of a promising series of previously synthesized quaternary ammonium (QASs) and phosphonium (QPSs) salts, which have shown potent activity against Staphylococcus aureus, including methicillin-resistant strains (MRSA).Methods and results The effects of QASs and QPSs on S. aureus surface charge, total surface hydrophobicity, intracellular potassium release, memb...
Seroprevalence of Protective Antibodies Against Influenza and the Reduction of ...
Guiomar, R; Pereira da Silva, S; Costa, I; Conde, P; Cristóvão, P; Rodrigues, AP; Fernandes, A; Dias, AP; Couto, AR; Ramos, A; Moita, C; Rodrigues, CBackground: Seroepidemiological studies provide estimates of population-level immunity, prevalence/incidence of infections, and evaluation of vaccination programs. We assessed the seroprevalence of protective antibodies against influenza and evaluated the correlation of seroprevalence with the cumulative annual influenza incidence rate. Methods: We conducted an annual repeated cross-sectional seroepidemiologica...
Association between area-level walkability and glycated haemoglobin: a Portugue...
Sá, R; Roquette, R; Rebecchi, A; Matias, J; Rocha, J; Buffoli, M; Capolongo, S; Ribeiro, AI; Nunes, B; Dias, C; Sousa Uva, MDiabetes poses a substantial disease burden, prompting preventive interventions. Physical inactivity, a major risk factor for type 2 diabetes, can potentially be mitigated by enhancing area-level walkability. Despite this, limited population-based studies have investigated the link between walkability and objective diabetes measures. Our study aims to estimate the association between area-level walkability and ...
Efficacy of Novel Quaternary Ammonium and Phosphonium Salts Differing in Cation...
Nunes, B; Cagide, F; Fernandes, C; Anabela Borges; Fernanda Borges; Simoes, M; Simões MAntibacterial resistance poses a critical public health threat, challenging the prevention and treatment of bacterial infections. The search for innovative antibacterial agents has spurred significant interest in quaternary heteronium salts (QHSs), such as quaternary ammonium and phosphonium compounds as potential candidates. In this study, a library of 49 structurally related QHSs was synthesized, varying the ...
Temporal change in minimum mortality temperature under changing climate A multi...
Yang, D; Hashizume, M; Tobías, A; Honda, Y; Roye, D; Oh, J; Dang, TN; Kim, Y; Abrutzky, R; Guo, Y; Tong, S; Coelho, MDSZS; Saldiva, PHN; Lavigne, EBackground: The minimum mortality temperature (MMT) or MMT percentile (MMTP) is an indicator of population susceptibility to nonoptimum temperatures. MMT and MMTP change over time; however, the changing directions show region-wide heterogeneity. We examined the heterogeneity of temporal changes in MMT and MMTP across multiple communities and in multiple countries. Methods: Daily time-series data for mortality a...
Temperature frequency and mortality: Assessing adaptation to local temperature
Wu, Y; Wen, B; Gasparrini, A; Armstrong, B; Sera, F; Lavigne, E; Li, S; Guo, Y; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AMAssessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and temperature from 757 locations in 47 countries/regions during 1979–2020. We used a two-stage time series design to assess the association between temperature frequency and all-cause mortality. The results were pooled ...
Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Tempera...
Hundessa, S; Huang, W; Zhao, Q; Wu, Y; Wen, B; Alahmad, B; Armstrong, B; Gasparrini, A; Sera, F; Tong, S; Madureira, J; Kyselý, J; Schwartz, JBackground: The association between nonoptimal temperatures and cardiovascular mortality risk is recognized. However, a comprehensive global assessment of this burden is lacking. Objectives: The goal of this study was to assess global cardiovascular mortality burden attributable to nonoptimal temperatures and investigate spatiotemporal trends. Methods: Using daily cardiovascular deaths and temperature data from...
Comparison for the effects of different components of temperature variability o...
Wen, B; Wu, Y; Guo, Y; Gasparrini, A; Tong, S; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM; Zanobetti, A; Analitis, A; Zeka, ABackground: Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. Objectives: We aimed to assess the association of intra-day TV and inter-day TV with all-cause, cardiovascular, and respiratory mortality. Methods: We collected data on total, cardiovascular, and respiratory mortality and meteorology from 758...
Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysi...
Robinson, L; Roccaldo, R; Rodrigues, D; Rodriguez Perez, MdC; Rodríguez Villamizar, LA; Rodríguez, AY; Roggenbuck, U; Rohloff, P; Rohner, FBackground: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods: We used data from 3663 population-based studies with 222 million participants that...