100 documents found, page 1 of 10
Assessment of the effects in mussels (Mytilus edulis) chronically exposed to en...
Motta, Eduardo; Neves , José; Gonçalves, José Fernando; Daniel, David; Nunes, Bruno; Correia, Alberto TeodoricoBackground: The presence of metallic nanoparticles (NP) in the aquatic environment is a cause for concern as they can have adverse effects on biota [1,2]. Objective: The purpose of this study was to evaluate the effect on mussels (Mytilus edulis) chronically exposed to environmentally realistic concentrations of nickel nanoparticles using oxidative stress and lipid peroxidation biomarkers. Methods: In this stud...
Investigating spatial-temporal contamination for two environments of the Amazon...
da Silva Montes, Caroline; Fernandes da Paixão, Leonardo; Nunes, Bruno; Pimentel Nunes, Zélia Maria; Pantoja Ferreira, Maria AuxiliadoraAn assessment of environmental quality in Amazonian estuaries utilizing histological and immunohistochemical biomarkers concomitantly with analyses of trace metals in the tissues of Sciades herzbergii, also considering physical chemical analyzes of the water. 352 animals were captured from two sites and during two periods (dry and rainy). Site 1: São Marcos Bay - heavy anthropic influence and Site 2: Caeté estu...
Toxicological effects resulting from co-exposure to nanomaterials and to a β-bl...
Silva, Paula Mayara Morais da; Alkimin, Gilberto Dias de; Camparotto, Natália Gabriele; Prediger, Patricia; Nunes, BrunoThe wide use of carbon-based materials for various purposes leads to their discharge in the aquatic systems, and simultaneous occurrence with other environmental contaminants, such as pharmaceutical drugs. This co-occurrence can adversely affect exposed aquatic organisms. Up to now, few studies have considered the simultaneous toxicity of nanomaterials, and organic contaminants, including pharmaceutical drugs, ...
Evaluation of parental and transgenerational effects of clotrimazole in Daphnia...
Ferreira, David; Alkimin, G. D.; Neves, Bruna; Conde, Tiago; Domingues, M. Rosário; Nunes, BrunoAzole antifungals inhibit the cytochrome P450 complex, decreasing the production of ergosterol in fungi, and compromising the biosynthesis of ecdysteroids in crustaceans, which are hormones regulating reproduction and ecdy-sis. The azole antifungal clotrimazole (CLO) raises environmental concerns due its toxicity. This work evaluated the effects on the number of moults, feeding rate, growth, reproduction, trans...
Investigation of potential behavioral and physiological effects of caffeine on ...
Nunes, Bruno; Santos, João; Dionísio, Ricardo; Dias de Alkimin, GilbertoWith the ever-increasing consumption of pharmaceutical compounds, their presence in the environment is now an undisputable reality. The majority of these compounds are released into the wild after their therapeutic use, as biotransformation products or in their original form. The presence of this class of compounds in the environment, due to their biological properties, can exert effects on non-target organisms...
Toxicity of two drugs towards the marine filter feeder Mytilus spp, using bioch...
Daniel, David; Campos, João C.; Costa, Paulo C.; Nunes, BrunoThe increasing presence of anthropogenic contaminants in the environment may constitute a challenge to non-target biota, considering that most contaminants can exert deleterious effects. Salicylic acid (SA) is a non-steroid anti-inflammatory drug (NSAID) which exerts its activity by inhibiting the enzyme cyclooxygenase (COX). Another class of drugs is that of the diuretics, in which acetazolamide (ACZ) is inclu...
A multi-biomarker approach for the early assessment of the toxicity of hospital...
Afsa, Sabrine; Vieira, Madalena; Nogueira, Ana Filipa; Mansour, Hedi Ben; Nunes, BrunoHospital wastewater (HWW) contains different hazardous substances resulting from a combination of medical and non-medical activities of hospitals, including pharmaceutical residues. These substances may represent a threat to the aquatic environment if they do not follow specific treatment processes. Therefore, we aimed to investigate the effects of the untreated effluent collected from a general hospital in Mah...
Assessment of paracetamol toxic effects under varying seawater pH conditions on...
Daniel, David; Nunes, Bruno; Pinto, Edgar; Ferreira, Isabel M. P. L. V. O.; Correia, Alberto TeodoricoIncreasing atmospheric carbon dioxide (CO2) levels are likely to lower ocean pH values, after its dissolution in seawater. Additionally, pharmaceuticals drugs are environmental stressors due to their intrinsic properties and worldwide occurrence. It is thus of the utmost importance to assess the combined effects of pH decreases and pharmaceutical contamination, considering that their absorption (and effects) ar...
Effect of sublethal concentrations of the antiparasitic ivermectin on the polyc...
Nunes, Bruno; Pinheiro, Diana; Gomes, AnaPharmaceutical drugs have emerged as major micropollutants in aquatic ecosystems. Their presence has been systematically reported in monitoring surveys, and their wide distribution and constant presence in the wild is a direct consequence of their massive use, in both human and veterinary therapeutics. Drugs used to treat parasitic infections in livestock are major contaminants, given the amounts in which they ...
Evaluation of single and combined effects of two pharmaceuticals on the marine ...
Daniel, David; Nunes, BrunoPharmaceutical drugs are among the most used chemicals for human and veterinary medicines, aquaculture and agriculture. Pharmaceuticals are environmentally persistent, biologically active molecules, thereby having the potential to exert biological effects on non-target species. Among the most used pharmaceuticals, one may find salicylic acid (SA), a non-steroid anti-inflammatory drug (NSAID) that acts by inhibi...