59 documents found, page 1 of 6
Paving the way for a non‐antibiotic and microbiota friendly therapy for Helicob...
Seabra, CL; Pinho, AS; Nunes, C; Amorim, I; Pedro, N; Henriques, P; Monteiro, C; Gomes, J; Machado, C; Gartner, F; Pereira, L; Reis, S; Reis, CABackground: The World Health Organization has identified Helicobacter pylori, a Gram-negative bacterium responsible for several gastric disorders, as one of the pathogenic bacteria that requires newer non-antibiotic approaches for its management. We previously demonstrated that nanostructured lipid carriers (NLC) loaded with docosahexaenoic acid (DHA-NLC)have excellent in vitro performance against H. pylori. Ma...
LOCUS (LOng Covid–Understanding Symptoms, events and use of services in Portuga...
Dinis Teixeira, JP; Santos, MJ; Soares, P; Azevedo, L; Barbosa, P; Vilas-Boas, A; Cordeiro, JV; Dias, S; Fonseca, M; Goes, AR; Lobão, MJ; Moniz, MApproximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COV...
Morphologic and Genetic Analysis of Synhimantus (Synhimantus) laticeps from a L...
Lopes, C; Santos-Silva, S; Nunes, C; Mendes, S; Costa, C; Brazio, E; Coutinho, T; Rodrigues, FT; Mesquita, JR; Coelho, AC; Cardoso, L; Lopes, APThe long-eared owl (Asio otus) is a medium-sized owl species that is well-distributed in almost all of the territories in Portugal. Nematodes were found in the oral cavity of a long-eared owl (A. otus) admitted to CRASSA (Wildlife Rehabilitation Centre of Santo Andre). During a physical exam and stabilization of the bird, five nematodes were collected. The worms were examined and measured under light microscopy...
Ecological factors associated with areas of high tuberculosis diagnosis delay
Soares, P; Aguiar, A; Leite, A; Duarte, R; Nunes, CObjective: We aimed to identify areas of high tuberculosis (TB) diagnosis delay in mainland Portugal in 2017 and ecological factors associated with these areas. Study design: This was an ecological study. Methods: We considered all notified pulmonary TB cases from the Portuguese National Tuberculosis Surveillance System in mainland Portugal. Diagnostic delays were calculated at the municipality level. Demograph...
How Charge, Size and Protein Corona Modulate the Specific Activity of Nanostruc...
Chitas, R; Nunes, C; Reis, S; Parreira, P; Martins, MCLThe major risk factor associated with the development of gastric cancer is chronic infection with Helicobacter pylori. The available treatments, based on a cocktail of antibiotics, fail in up to 40% of patients and disrupt their gut microbiota. The potential of blank nanostructured lipid carriers (NLC) for H. pylori eradication was previously demonstrated by us. However, the effect of NLC charge, size and prote...
Lower prevalence of congenital cytomegalovirus infection in Portugal: possible ...
Fernandez, C; Chasqueira, MJ; Marques, A; Rodrigues, L; Marçal, M; Tuna, M; Braz, MC; Neto, AS; Mendes, C; Lito, D; Rocha, P; Vasconcellos, GCytomegalovirus (CMV) is the most frequent cause of congenital infection all over the world. Its prevalence ranges from 0.2 to 2.2%. Transmission from children to their pregnant mothers is a well-known risk factor, particularly if they attend a childcare centre. This study aims to compare the prevalence of CMV congenital infection (CMV_CI) in Portugal (Lisbon) between two studies, performed respectively in 2019...
Driving factors for the utilisation of healthcare services by people with osteo...
Costa, D; Rodrigues, AM; Cruz, EB; Canhão, H; Branco, J; Nunes, CBackground: Worldwide, the current management of knee osteoarthritis appears heterogeneous, high-cost and often not based on current best evidence. The absence of epidemiological data regarding the utilisation of healthcare services may conceal the need for improvements in the management of osteoarthritis. The aim of this study is to explore the profiles of healthcare services utilisation by people with knee os...
Factors Associated With Clinical and Radiographic Severity in People With Osteo...
Costa, D; Cruz, EB; Silva, C; Canhão, H; Branco, J; Nunes, C; Rodrigues, AMBackground: Hip/knee osteoarthritis (HKOA) is a leading cause of disability and imposes a major socioeconomic burden. The aim of this study is to estimate the prevalence of HKOA in Portugal, characterised the clinical severity of HKOA in the population, and identified sociodemographic, lifestyle, and clinical factors associated with higher clinical and radiographic severity. Methods: Participants with a diagnos...
A Case-Control Study of Contextual Factors for SARS-CoV-2 Transmission
Leite, A; Leão, T; Soares, P; Severo, M; Moniz, M; Lucas, R; Aguiar, P; Meireles, P; Lunet, N; Nunes, C; Barros, HBackground: Knowledge on the settings and activities associated with a higher risk of SARS-CoV-2 transmission is essential to inform decision-making. We thus designed a case-control study to identify relevant settings for community transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Portugal. Methods: We evaluated 1,088 cases, identified through the national surveillance system, and ...
Are Data from Mycotoxins' Urinary Biomarkers and Food Surveys Linked? A Review ...
Martins, C; Assunção, R; Nunes, C; Torres, Duarte; Alvito, PMycotoxins are natural chemical contaminants of foods, posing several health risks to humans. Biomarkers-driven research has been used as a tool for a more accurate characterization of the internal exposure. Whether certain food items are predictors of exposure to mycotoxins constitutes an important aspect for the risk assessment of mycotoxins. Comprehensive human biomonitoring studies linked with food surveys ...