8 documents found, page 1 of 1
Concepts for the development of person-centred, digitally-enabled, Artificial I...
Bousquet, J; Schünemann, HJ; Sousa-Pinto, B; Zuberbier, T; Togias, A; Samolinski, B; Bedbrook, A; Czarlewski, W; Hofmann-Apitius, M; Litynska, JThe traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own life based on their lived experiences. Improving healthcare safety, quality and coordination, as well as quality of life, are important aims in the care of patients with chronic conditions. Person-centred care needs to ensure that people's v...
Rhinitis Associated with Asthma is Distinct from Rhinitis Alone: The ARIA‐MeDAL...
Bousquet, J; Melén, E; Haahtela, T; Koppelman, GH; Togias, A; Valenta, R; Akdis, CA; Czarlewski, W; Rothenberg, M; Valiulis, A; Wickman, M; Akdis, MAsthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...
Issue 1 - “Update on adverse respiratory effects of outdoor air pollution” Part...
Sousa, AC; Pastorinho, MR; Masjedi, MR; Urrutia-Pereira, M; Arrais, M; Nunes, E; To, T; Ferreira, AJ; Robalo-Cordeiro, C; Borrego, C; Teixeira, JPObjective: To analyse the GARD perspective on the health effects of outdoor air pollution, and to synthesise the Portuguese epidemiological contribution to knowledge on its respiratory impact. Results: Ambient air pollution has deleterious respiratory effects which are more apparent in larger, densely populated and industrialised countries, such as Canada, Iran, Brazil and Portugal, but it also affects people l...
The occurrence of accidents and injury in mining shift worker influenced by foo...
Andaque, GA; Pinho, Olívia; Baptista, JS; Castelo Branco, J; Nunes, E<jats:p>Introduction: Identifying factors that contribute to occupational accidents has been a general concern of companies in the present millennium. One of the factors identified is the quality and quantity of food, as well as meals times. In this context, the present systematic review aimed to identify how food intake influences the occurrence of accidents in shift work, with some focus, although not exclusi...
Febre na Criança: Pais e Enfermeiros, Parceiros nos Cuidados
Zeferino, L; Nunes, EA febre é uma manifestação muito frequente e por vezes inespecífica na criança, que motiva frequentemente a ida a um serviço de urgência e o internamento (National Institute for Health and Clinical Excellence, 2007). Está por vezes associada a morbilidade e mortalidade, sobretudo em crianças com menos de 5 anos, contudo, nem sempre expressa uma doença. Este facto justifica, por um lado, a preocupação dos pais e...
Antioxidant and vascular effects of gliclazide in type 2 diabetic rats fed high...
Sena, CM; Louro, T; Matafome, P; Nunes, E; Monteiro, P; Seiça, RDiabetes mellitus is characterized by oxidative stress, which in turn determines endothelial dysfunction. Gliclazide is a sulphonylurea antidiabetic drug with antioxidant effects due to its azabicyclo-octyl ring. It has been reported to potentially protect the vasculature through improvements in plasma lipid levels and platelet function. We hypothesized that gliclazide has a beneficial effect on endothelial fun...
A role for atorvastatin and insulin combination in protecting from liver injury...
Matafome, P; Nunes, E; Louro, T; Amaral, C; Crisóstomo, J; Rodrigues, L; Moedas, AR; Monteiro, P; Cipriano, MA; Seiça, RNon-alcoholic fatty liver disease (NAFLD) is a major complication linked with the metabolic syndrome associated with dyslipidemia, inflammation, and oxidative stress. Impact of type 2 diabetes with hyperlipidemia in NAFLD has to be established, as well as the utility of commonly prescribed anti-diabetic and lipid-lowering agents in improving liver injury markers. Genetic type 2 diabetic Goto-Kakizaki rats were ...
Disfunção Endotelial na Diabetes Tipo 2: Efeito de Antioxidantes
Sena, CM; Nunes, E; Louro, T; Proença, T; Seiça, RMIndividuals with insulin resistance and diabetes mellitus have increased cardiovascular morbidity and mortality, caused in part by vascular complications. Endothelial dysfunction has been implicated in the pathogenesis of vascular diabetic disease. This abnormal function of the vasculature precedes cardiovascular disease and is associated with impaired endothelium-dependent vasorelaxation. The main etiology of ...