20 documents found, page 1 of 2
Chronic Intestinal Failure and Short Bowel Syndrome in Adults: The State of the...
Vara-Luiz, F; Glória, L; Mendes, I; Carlos, S; Guerra, P; Nunes, G; Oliveira, CS; Ferreira, A; Santos, AP; Fonseca, JBackground: Short bowel syndrome (SBS) is a devastating malabsorptive condition and the most common cause of chronic intestinal failure (CIF). During the intestinal rehabilitation process, patients may need parenteral support for months or years, parenteral nutrition (PN), or hydration/electrolyte supplementation, as a bridge for the desired enteral autonomy. Summary: Several classification criteria have been h...
A Unique Case of Recurrent Upper Gastrointestinal Bleeding Caused by Two Metach...
Brito, M; Nunes, G; Pinto Marques, P; Canhoto, M; Proença, AL; Fonseca, JIntroduction: Dieulafoy's lesion (DL) is a rare but important cause of acute, severe, life-threatening, and recurrent upper gastrointestinal bleeding (UGIB). It is frequently difficult to diagnose DL with upper GI endoscopy (UGIE), and endoscopic ultrasonography (EUS) may be valuable. There are only 2 reported bleeding cases caused by two synchronous DL but no reported cases of two metachronous DL. Case report:...
Association Between Memory B-Cells and Clinical and Immunological Features of P...
Barcelos, F; Martins, C; Papoila, A; Geraldes, C; Cardigos, J; Nunes, G; Lopes, T; Alves, N; Vaz-Patto, J; Branco, J; Borrego, LMB-cells play a pivotal role in primary Sjögren's syndrome (pSS) pathogenesis. We aim to (1) evaluate the distribution of B-lymphocyte subpopulations in pSS and Sicca patients, (2) establish cut-off points that discriminate pSS from controls, (3) evaluate the association between memory B-cells and phenotypic features in pSS. We included 57 pSS patients, 68 Sicca and 24 healthy controls. Circulating B-cells were ...
Impact of Labor on Peripheral Blood Maternal T-Cell Subsets and on Regulatory T...
Lima, J; Martins, C; Nunes, G; Sousa, MJ; Branco, J; Borrego, LLabor is thought to positively influence immune system development in the offspring, but studies investigating the impact of different modes of delivery on maternal immune system cells are scarce. Therefore, the aim of this study was to investigate the effect of labor on maternal peripheral blood T-cell subsets and on the recently described regulatory T and B cells. METHODS: Cross-sectional study comparing the ...
Regulatory T Cells Show Dynamic Behavior During Late Pregnancy, Delivery, and t...
Lima, J; Martins, C; Nunes, G; Sousa, MJ, et al.Regulatory T cells (Tregs) are critical immunomodulators during early pregnancy by preventing maternal T-cell activation against fetal cells. However, how populations of maternal Tregs vary during and after pregnancy in humans is still unclear. Therefore, we investigated Treg subsets in the peripheral blood of pregnant women from late pregnancy through the postpartum period. To accomplish this, the following ci...
Characterization of B cells in healthy pregnant women from late pregnancy to po...
Lima, J; Martins, C; Leandro, MJ; Nunes, G; Sousa, MJ; Branco, J; Borrego, LMBACKGROUND: B cells play a role in pregnancy due to their humoral and regulatory activities. To our knowledge, different maturational stages (from transitional to memory) of circulating B cell subsets have not yet been characterized (cell quantification and phenotype identification) in healthy pregnant women. Thus, the objective of our study was to characterize these subsets (as well as regulatory B cells) from...
Hepatite Tóxica Induzida por Produtos Fitoterapêuticos: Natural Não é Sinónimo ...
Serrano Ferreira, B; Neiva, J; Nunes, G; Barata, JA case of toxic hepatitis induced by a fat burner natural product is reported. Pathogenic mechanisms of hepatotoxicity arediscussed, and causality nexus is analyzed. The goal of this presentation is to alert for the risk of severe adverse events while consuming falsely harmless products.
Regulatory T and B cells in asthmatic women: variations from pregnancy to postp...
Martins, C; Lima, J; Nunes, G; Borrego, LMBACKGROUND: Allergic asthma and rhinitis are common in pregnancy. The immune mechanisms underlying the effects of pregnancy in asthma and vice-versa are not completely understood. OBJECTIVES: This work aimed to study the evolution of regulatory T and B cells in asthmatic pregnant women, from late pregnancy till postpartum. METHODS: Four groups of women were enrolled for this study: third trimester pregnant wome...
Characterization of B cells in healthy pregnant women from late pregnancy to po...
Lima, J; Martins, C; Leandro, MJ; Nunes, G; Sousa, MJ; Branco, JC; Borrego, LMBACKGROUND: B cells play a role in pregnancy due to their humoral and regulatory activities. To our knowledge, different maturational stages (from transitional to memory) of circulating B cell subsets have not yet been characterized (cell quantification and phenotype identification) in healthy pregnant women. Thus, the objective of our study was to characterize these subsets (as well as regulatory B cells) from...
Characterization of B cells in healthy pregnant women from late pregnancy to po...
Lima, J; Martins, C; Leandro, MJ; Nunes, G; Sousa, MJ; Branco, JC; Borrego, LMAbstract BACKGROUND: B cells play a role in pregnancy due to their humoral and regulatory activities. To our knowledge, different maturational stages (from transitional to memory) of circulating B cell subsets have not yet been characterized (cell quantification and phenotype identification) in healthy pregnant women. Thus, the objective of our study was to characterize these subsets (as well as regulatory B ce...