3 documents found, page 1 of 1
Acetylcholine release and choline uptake by cuttlefish (Sepia officinalis) opti...
Nunes, M. Alexandra; Santos, Sofia; Cordeiro, J. Miguel; Neves, Paulo; Silva, Virgilia S.; Sykes, Antonio; Morgado, Fernando; Dunant, YvesAcetylcholine (ACh), which is synthesized from choline (Ch), is believed to hold a central place in signaling mechanisms within the central nervous system (CNS) of cuttlefish (Sepia officinalis) and other coleoid cephalopods. Although the main elements required for cholinergic function have been identified in cephalopods, the transmembrane translocation events promoting the release of ACh and the uptake of Ch r...
Acetylcholine release and choline uptake by cuttlefish (Sepia officinalis) opti...
Nunes, M. Alexandra; Santos, Sofia; Cordeiro, J. Miguel; Neves, Paulo; Silva, Virgília S.; Sykes, António V.; Morgado, Fernando; Dunant, YvesAcetylcholine (ACh), which is synthesized from choline (Ch), is believed to hold a central place in signaling mechanisms within the central nervous system (CNS) of cuttlefish (Sepia officinalis) and other coleoid cephalopods. Although the main elements required for cholinergic function have been identified in cephalopods, the transmembrane translocation events promoting the release of ACh and the uptake of Ch r...
Comparative effects of aluminum and ouabain on synaptosomal choline uptake, ace...
Silva, Virgília S.; Nunes, M. Alexandra; Cordeiro, J. Miguel; Calejo, Ana I.; Santos, Sofia; Neves, Paulo; Sykes, António V.; Morgado, FernandoClosing the gap between adverse health effects of aluminum and its mechanisms of action still represents a huge challenge. Cholinergic dysfunction has been implicated in neuronal injury induced by aluminum. Previously reported data also indicate that in vivo and in vitro exposure to aluminum inhibits the mammalian (Na(+)/K(+))ATPase, an ubiquitous plasma membrane pump. This study was undertaken with the specifi...