2 documents found, page 1 of 1
Treatment of Chagas cardiomyopathy.
Botoni, Fernando Antônio; Ribeiro, Antônio Luiz Pinho; Marinho, Carolina Coimbra; Lima, Marcia Maria Oliveira; Nunes, Maria do Carmo PereiraChagas’ disease (ChD), caused by the protozoa Trypanosoma cruzi (T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still bringsmuch misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in South America. It is an increasing worldwide problem due to t...
Low levels of vasoactive intestinal peptide are associated with Chagas disease ...
Corrêa, Marielle Valério; Rocha, Manoel Otávio da Costa; Sousa, Giovane Rodrigo de; Nunes, Maria do Carmo Pereira; Gollob, Kenneth JohnThe interconnection between immune and neuroendocrine systems influences regulation of inflammatory responses. The possible relevance that this integrative response may have during the course of Chagas disease remains poorly characterized. In this context, our study was designed to determine the expression of vasoactive intestinal peptide (VIP), a neuropeptide with anti-inflammatory properties, in blood from th...