The preservation of natural stone heritage is still a major challenge for the scientific community. This topic assumes a greater importance since it impacts economic and socio-cultural values. Recent research has indicated that water action and microorganism activity are among the major contributors to the deterioration of this material. Despite the emergence of new protective solutions in the market, some cons...
Introdução: O Mestrado Integrado em Medicina da Faculdade de Medicina e Ciências Biomédicas da Universidade do Algarve, desde a sua génese, que foi descrito como um curso inovador em termos pedagógicos. O plano de estudos baseia-se na aprendizagem através de casos clínicos, adaptando-se assim às novas evoluções da educação médica internacional. Relativamente ao processo de seleção ao curso, este é composto por ...
The biological activity of A. unedo leaves, in relation to their traditional medicinal use in treating gastrointestinal and urinary tract diseases was verified. The ethanol extract of the leaves was quantitatively described in terms of flavonoids and phenolic acids (RP-HPLC), and zinc (voltametric analysis) and subjected to cytotoxic (MTT), antioxidant (TPC, TFC, TAA, RP, DPPH, and FRAP), antibacterial (disc di...
Objective: Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous studies in HD, in this study we aim to investigate in vitro in a neuroblastoma cellular model of HD, the effect of CYP46A1 overexpression, an essential enzyme in cholesterol metabolism, on hunti...
Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous studies in HD, in this study we aim to investigate in vitro in a neuroblastoma cellular model of HD, the effect of CYP46A1 overexpression, an essential enzyme in cholesterol metabolism, on huntin...
A afirmação de poder, tão velha quanto a história da humanidade, tão dispersa nas suas formas e rostos, tão abrangente nos territórios e ambições, faz do seu intuito um pendulo permanente e incansável. O Quarto Poder, tema eleito para a presente proposta, é vizinho do poder político, judicial e executivo, e quantas vezes denominado por “Contrapoder”, “Equilíbrio entre os Poderes” e “Poder Moderador”. Hoje, na e...
The catalytic behaviour of hierarchical BEA zeolites with Si/Al ratio of 12.5 and 32 was studied in Friedel-Crafts acylation reactions using furan, anisole and pyrrole as substrates and acetic anhydride as acylating agent. Hierarchical BEA samples were submitted to alkaline and alkaline + acid treatments. Kinetic modelling using nonlinear regressions applied to a simplified Langmuir-Hinshelwood equation showed ...
The catalytic behaviour of hierarchical BEA zeolites with Si/Al ratio of 12.5 and 32 was studied in Friedel-Crafts acylation reactions using furan, anisole and pyrrole as substrates and acetic anhydride as acylating agent. Hierarchical BEA samples were submitted to alkaline and alkaline + acid treatments. Kinetic modelling using nonlinear regressions applied to a simplified Langmuir-Hinshelwood equation showed ...