26 documents found, page 1 of 3
White matter alterations in episodic migraine without aura patients assessed wi...
Guadilla, Irene; Fouto, Ana R.; Ruiz-Tagle, Amparo; Esteves, Inês; Caetano, Gina; Silva, Nuno A.; Vilela, Pedro; Gil-Gouveia, RaquelObjective To assess the efect of modeling free water (FW) on the identifcation of white matter (WM) microstructure alterations using difusion Magnetic Resonance Imaging (dMRI) in episodic migraine without aura patients compared with healthy controls. Background Difusion tensor imaging (DTI) studies examining WM in migraine patients previously overlooked the potential infuence of FW partial volume efects. Correc...
Alterations of white matter microstructure in migraine patients vary in the per...
Fouto, Ana R.; Nunes, Rita G.; Guadilla, Irene; Ruiz-Tagle, Amparo; Esteves, Inês; Caetano, Gina; Silva, Nuno A.; Vilela, Pedro; Gil-Gouveia, RaquelAlterations in white matter (WM) microstructure are commonly found in migraine patients. Here, we employ a longitudinal study of episodic migraine without aura using diffusion magnetic resonance imaging (dMRI) to investigate whether such WM microstructure alterations vary through the different phases of the pain cycle. Fourteen patients with episodic migraine without aura related with menstruation were scanned ...
Uncovering longitudinal changes in the brain functional connectome along the mi...
Esteves, Inês; Fouto, Ana R.; Ruiz-Tagle, Amparo; Caetano, Gina; Nunes, Rita G.; Silva, Nuno A. da; Vilela, Pedro; Martins, Isabel PavãoChanges in large-scale brain networks have been reported in migraine patients, but it remains unclear how these manifest in the various phases of the migraine cycle. Case-control fMRI studies spanning the entire migraine cycle are lacking, precluding a complete assessment of brain functional connectivity in migraine. Such studies are essential for understanding the inherent changes in the brain of migraine pati...
Uncovering longitudinal changes in the brain functional connectome along the mi...
Esteves, Inês; Fouto, Ana R.; Ruiz-Tagle, Amparo; Caetano, Gina; Nunes, Rita G.; da Silva, Nuno A.; Vilela, Pedro; Martins, Isabel PavãoBackground: Changes in large-scale brain networks have been reported in migraine patients, but it remains unclear how these manifest in the various phases of the migraine cycle. Case-control fMRI studies spanning the entire migraine cycle are lacking, precluding a complete assessment of brain functional connectivity in migraine. Such studies are essential for understanding the inherent changes in the brain of m...
Involvement of the cerebellum in structural connectivity enhancement in episodi...
Matoso, Ana; Fouto, Ana R.; Esteves, Inês; Ruiz-Tagle, Amparo; Caetano, Gina; Silva, Nuno A. da; Vilela, Pedro; Gil-Gouveia, Raquel; Nunes, Rita G.Background: The pathophysiology of migraine remains poorly understood, yet a growing number of studies have shown structural connectivity disruptions across large-scale brain networks. Although both structural and functional changes have been found in the cerebellum of migraine patients, the cerebellum has barely been assessed in previous structural connectivity studies of migraine. Our objective is to investig...
Impact of truncating diffusion MRI scans on diffusional kurtosis imaging
Fouto, Ana R.; Henriques, Rafael N.; Golub, Marc; Freitas, Andreia C.; Ruiz-Tagle, Amparo; Esteves, Inês; Gil-Gouveia, Raquel; Silva, Nuno A.Objective Difusional kurtosis imaging (DKI) extends difusion tensor imaging (DTI), characterizing non-Gaussian difusion efects but requires longer acquisition times. To ensure the robustness of DKI parameters, data acquisition ordering should be optimized allowing for scan interruptions or shortening. Three methodologies were used to examine how reduced difusion MRI scans impact DKI histogram-metrics: 1) the el...
Editorial for “Three‐dimensional multifrequency MR elastography for microvascul...
Adubeiro, Nuno; Nunes, Rita G.; Nogueira, LuísaThe prognosis of individuals with hepatocellular carcinoma(HCC), the most prevalent primary liver malignancy, is closely linked to the aggressiveness and recurrence of the tumor. The occurrence of complications after surgery continues to be a major and persistent challenge. MR elastography (MRE) employs a modified phase-contrast imaging sequence, combined with the use of an external driver to transmit mechanical...
Editorial for “3D breast cancer segmentation in DCE‐MRI using deep learning wit...
Nogueira, Luísa; Adubeiro, Nuno; Nunes, Rita G.Magnetic resonance imaging (MRI) shows higher diagnostic performance in the detection of breast tumors, compared with other imaging modalities. Breast MRI protocols include dynamic contrast-enhanced (DCE) images with high spatial and temporal resolution and are central indiagnosis, staging, and follow-up of breast cancer. DCE features provide physiological and anatomical lesion characteristics. To extract these...
Impact of susceptibility-induced distortion correction on perfusion imaging by ...
Domingos, Catarina; Fouto, Ana R.; Nunes, Rita G.; Ruiz-Tagle, Amparo; Esteves, Inês; Silva, Nuno A.; Vilela, Pedro; Gil-Gouveia, RaquelPurpose: The consensus for the clinical implementation of arterial spin labeling (ASL) perfusion imaging recommends a segmented 3D Gradient and Spin-Echo (GRASE) readout for optimal signal-to-noise-ratio (SNR). The correction of the associated susceptibility-induced geometric distortions has been shown to improve diagnostic precision, but its impact on ASL data has not been systematically assessed and it is not...
Impact of white-matter mask selection on DTI histogram-based metrics as potenti...
Rodrigues Fouto, Ana Lúcia; Nunes, Rita G.; Pinto, Joana; Alves, Luísa; Calado, Sofia; Gonçalves, Carina; Rebolo, Margarida; Viana Baptista, MiguelObjective: Histogram-based metrics extracted from diffusion-tensor imaging (DTI) have been suggested as potential biomarkers for cerebral small vessel disease (SVD), but methods and results have varied across studies. This work aims to assess the impact of mask selection for extracting histogram-based metrics of fractional anisotropy (FA) and mean diffusivity (MD) on their sensitivity as SVD biomarkers. Methods...