36 documents found, page 1 of 4

“Can I have more ideas?” - developing soft skills in secondary education childr...

This paper investigates the effectiveness of integrating design thinking methodologies into elementary education to foster soft skills among children aged 9 to 10. There is a widening gap in soft skills among younger generations, particularly when first entering the workplace. Therefore, the study explores the impact of design thinking interventions on seven key soft skills: teamwork, empathy, communication, sy...

Determinants of HIV-1 Transmission Clusters and Transmitted Drug Resistance in ...

Introduction: In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determina...

Supervisão pedagógica: uma ferramenta para uma educação de infância inclusiva e...

A educação de infância desempenha um papel fundamental no desenvolvimento das crianças, uma vez que é neste período que se estabelecem os pilares fundamentais para a aquisição e consolidação das aprendizagens. Por esse motivo, torna-se indispensável garantir que as práticas pedagógicas sejam de qualidade, inclusivas – conscientes dos diferentes tipos e formas de discriminação – e promotoras de igualdade de opor...

The contribution of genetics to the understanding and management of cardiomyopa...

Genetics has assumed a pivotal role in clarifying the pathophysiology of cardiomyopathies, facilitating molecular diagnosis, and enabling effective family screening. The advent of next-generation sequencing has revolutionized genetic testing by enabling cost-effective, high-throughput analysis. It is imperative for cardiovascular physicians to mainstream genetic testing into their clinical decision-making. Alth...

Determinants of HIV-1 transmission clusters and transmitted drug resistance in ...

In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determinants in MSM new...

Supervisão pedagógica: uma ferramenta para uma educação de infância inclusiva e...

A educação de infância desempenha um papel fundamental no desenvolvimento das crianças, uma vez que é neste período que se estabelecem os pilares fundamentais para a aquisição e consolidação das aprendizagens. Por esse motivo, torna-se indispensável garantir que as práticas pedagógicas sejam de qualidade, inclusivas - conscientes dos diferentes tipos e formas de discriminação - e promotoras de igualdade de opor...

Determinants of HIV late presentation among men who have sex with men in Portug...

Introduction: HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019. Methods: We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral q...

Faces de Eva : Revista de Estudos sobre a Mulher (2024) N.º 50

Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hal...

Cholesterol 24-hydroxylase (CYP46A1) is an exclusively neuronal cytochrome P450 enzyme responsible for converting cholesterol into 24S-hydroxycholesterol, which serves as the primary pathway for eliminating cholesterol in the brain. We and others have shown that increased activity of CYP46A1 leads to reduced levels of cholesterol and has a positive effect on cognition. Therefore, we hypothesized that CYP46A1 co...

Determinants of HIV late presentation among men who have sex with men in Portug...

Introduction HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019.Methods We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral ques...