60 documents found, page 1 of 6
An integrative review of potential diagnostic biomarkers for complex regional p...
Lopes, Revelino; Santos, André; Gomes, Teresa; Ribeiro, Júlia; Rodrigues, Ivone; Paiva, Bruno; Nzwalo, Isa; Catamo Vaz, Deise Haua da Silva; Baco, JamalBackground: Complex regional pain syndrome (CRPS) is a rare, chronic, painful, neurological, debilitating disorder. Despite the substantial impact on quality of life, diagnosis remains challenging due to its complex pathophysiology and subjective clinical criteria. This integrative review aims to synthesize current research on potential diagnostic biomarkers for CRPS. Methods: A systematic search was conducted ...
Clinical and epidemiological characteristics of patients with functional stroke...
Figueira Domingos, Miguel; Silva, Vítor Hugo; Schuh, Sara; Correia, Helena; Palma, Pedro; Pedro, João Pedroso; Nova, Bruno Vila; Marreiros, AnaBackground: Patients with functional neurological disorder presenting as stroke mimics or functional stroke mimics (FSMs) pose significant diagnostic challenges. In the acute phase, especially when patients are present within the therapeutic window for acute reperfusion treatments, a misdiagnosis of FSM can lead to unnecessary and costly interventions. Despite its clinical importance, the literature on the risk...
Prognostic Factors Associated with Disability in a Cohort of Neuromyelitis Opti...
Moura, João; Samões, Raquel; Sousa, Ana Paula; Figueiroa, Sónia; Mendonça, Teresa; Abreu, Pedro; Guimarães, Joana; Melo, Claúdia; Sousa, RaquelIntroduction: Neuromyelitis optica spectrum disorders (NMOSD) and MOG-associated disease (MOGAD) are an increasingly recognized group of demyelinating disorders of the central nervous system. Previous studies suggest that prognosis is predicted by older age at onset, number of relapses, the severity of the first attack and autoantibody status. Objective: To study prognostic factors associated with disability pr...
Possible role of mycotoxins, malnutrition and MECP2 dysregulation in nodding sy...
Catamo Vaz, Deise Haua da Silva; Costa, Maria Helena da; Buque, Helena Agostinho; Nzwalo, HipólitoWe read with great interest the manuscript by Spencer et al. [1] suggesting a possible role of Methyl-CpG-binding protein 2 (MECP2) dysregulation in the pathogenesis of Nodding syndrome (NS), a childhood onset epileptic disorder occurring exclusively in sub-Saharan Africa. The sociodemographic and phenotypic overlap of NS with MECP2 duplication syndrome, namely the age of onset interval, female predominance;
Establishment of an induced pluripotent cell line (ABCRIi001-A) from an elderly...
Esteves, Filipa; Vilhena Catarino Brito, David; Rajado, Ana Teresa; Silva, Nádia; Apolónio, Joana; Roberto, Vânia; Andrade, Raquel; Calado, SofiaHuman induced pluripotent stem cells (hiPSCs) hold promises to model and understand human diseases, including those associated with ageing. Here, we describe ABCRIi001-A, a hiPSC line generated from peripheral blood mononuclear cells (PBMCs) of a 79-year-old female enrolled in a study for development of an ageing score (ALFA Score). PBMCs were reprogrammed using three Sendai virus-based reprogramming vectors (h...
From spinal ependymoma to superficial siderosis: a bottom to top cause of progr...
Valente, Diana; Felix, Catarina; Nzwalo, Hipólito; Gil, InêsSuperficial siderosis (SS) is an infrequent condition characterized by hemosiderin deposition in the central nervous system, resulting from chronic subarachnoid hemorrhage, often linked to dural mater diseases. Through a case report of a 50-year-old male with severe sensorineural hearing loss and newly diagnosed epilepsy, we explore SS triggered by a spinal ependymoma, diagnosed via resonance magnetic imaging (...
RCO-1 O PAPEL DO BACKGROUND ACADÉMICO NA PERFORMANCE DOS ALUNOS DO MIM-UALG: DA...
de Almeida, Tomás; Nzwalo, Hipólito; Afonso, Ricardo; Nunes, Sofia; Marreiros, AnaIntrodução: O Mestrado Integrado em Medicina da Universidade do Algarve (MIM- UAlg) apresenta uma estrutura curricular única, humanista e integralmente baseada em casos clínicos, adaptando-se assim às novas evoluções da educação médica internacional 1,2. Correlacionando este plano curricular com o perfil dos seus estudantes, apresenta um modelo de seleção baseado em provas cognitivas e mini-múltiplas entrevista...
RCO-4 PERFIL DE CUIDADOR E IMPACTO NO PERCURSO ACADÉMICO DOS ESTUDANTES MIM-UALG
Margarido, Marta; Nzwalo, Hipólito; Afonso, Ricardo; Nunes, Sofia; Marreiros, AnaIntrodução: As habilidades não cognitivas têm vindo a destacar-se na admissão de candidatos ao curso de medicina e a ser cada vez mais estudadas em contexto académico. Estas são avaliadas por escolas médicas, através de mini-entrevistas múltiplas (MMI), que permitem selecionar os atributos pessoais necessários para um profissional de saúde competente.1 Academicamente, a personalidade de estudantes de medicina t...
RP-14 MINI-ENTREVISTAS MÚLTIPLAS: CONDICIONANTES E ASSOCIAÇÃO COM O DESEMPENHO ...
Marques, Ana Cláudia; Nzwalo, Hipólito; Afonso, Ricardo; Nunes, Sofia; Marreiros, AnaIntrodução: O Mestrado Integrado em Medicina da Universidade do Algarve (MIM-UAlg), utiliza mini-entrevistas múltiplas (MEM) na seleção dos seus alunos pós-graduados. Cada MEM avalia diferentes domínios, nomeadamente: responsabilidade; julgamento ético e moral; comunicação; competências de gestão; resolução de problemas; autoconsciência; trabalho de equipa; resolução de conflitos. Objetivos: Dada a importância...
RP-15 CHARACTERISATION OF PERSONALITY DIMENSIONS OF MIM-UALG STUDENTS IN A 3 ME...
Galinha, Catarina; Nzwalo, Hipólito; Neto, Isabel; Afonso, Ricardo; Nunes, Sofia; Marreiros, AnaObjectives: Given the specificity of Algarve University, as the only medical school in the country with exclusively postgraduate program, it is relevant to make the assessment of personality traits that characterise its medical students, and compare it with two other national medical schools. Methods: NEO-FII was the selected instrument to assess personality dimensions. NEO- FII was applied only once, to studen...