7 documents found, page 1 of 1
Low-dose ionizing radiation induces therapeutic neovascularization in a pre-cli...
Ministro, Augusto; Oliveira, Paula de; Nunes, Raquel J.; Rocha, André dos Santos; Correia, Adriana; Carvalho, Tânia; Rino, José; Faísca, PedroAims: We have previously shown that low-dose ionizing radiation (LDIR) induces angiogenesis but there is no evidence that it induces neovascularization in the setting of peripheral arterial disease. Here, we investigated the use of LDIR as an innovative and non-invasive strategy to stimulate therapeutic neovascularization using a model of experimentally induced hindlimb ischemia (HLI). Methods and results: Afte...
Evaluation of the corpus callosum by MRI related to the frontal atrophy in the ...
Ribeiro, Margarida; O'Neill, João Goyri; Maurício, J. CruzPurpose: The thinning of the corpus callosum (CC) is a sign of brain changes related to age. The use of quantitative methods can help to discriminate the pathological cerebral atrophy from the normal brain aging. This study aimed to quantify the atrophy of frontal lobe in subjects with the age recoded in [< 65 and ≥66] years old and to investigate its relationship with the dimensions (length and volume) of the ...
Substância branca no cérebro do idoso “bem-sucedido”: avaliação do coeficiente ...
Ribeiro, Margarida; Maurício, J. Cruz; O'Neill, João GoyriNa literatura, os valores das métricas da Diffusion Weighthed Imaging (DWI) não são consensuais. Tanto se relata que o coeficiente aparente de difusão (ADC) é uma medida quantitativa das alterações microestruturais e um marcador sensível às alterações precoces no idoso, como a perda de mielina, como existem outros estudos que contrariam a teoria da senescência da substância branca (SB) e indicam que o ADC não é...
Optimising protocol of acquisition and post-processing procedures in the assess...
Ribeiro, Margarida; Gonçalves, Nuno Caldeira; Bate, Inês Baião; O'Neill, João Goyri; Maurício, J. CruzCoronary artery disease (CAD) is currently one of the most prevalent diseases in the world population and calcium deposits in coronary arteries are one direct risk factor. These can be assessed by the calcium score (CS) application, available via a computed tomography (CT) scan, which gives an accurate indication of the development of the disease. However, the ionising radiation applied to patients is high. Thi...
Caraterização da tecnologia por ressonância magnética em Portugal
Ribeiro, Margarida; O'Neill, João Goyri; Maurício, J. CruzA imagem por Ressonância Magnética (RM) invadiu os cenários clínicos a partir da segunda metade dos anos 80 e comparativamente aos métodos de imagem por Raios X (Rx) ofereceu uma notável combinação entre segurança, quanto à exposição às radiações ionizantes, elevadas resolução espacial e de contraste, no que se refere à qualidade de imagem e, enquanto teste de diagnóstico, uma multifacetada sensibilidade e espe...
Vertebral metrics: application of a mechanical instrument to evaluate the spina...
Quaresma, Cláudia; Fonseca, Miguel; Secca, Mario Forjaz; O'Neill, João Goyri; Branco, JorgeThe published literature about the biomechanical alterations of the spinal column during pregnancy is scarce and disperses, being more qualitative and limited to partial analysis of the spinal column. The main justification for a global approach to be neglected could be related to the inexistence of a non-invasive instrument that evaluates the spinal column in an objective and complete way. Thus, in order to fi...
Comparative evaluation of the tridimensional spine position measured with a new...
Quaresma, Cláudia; Joao, Filipa; Fonseca, Miguel; Secca, Mário Forjaz; Veloso, António Prieto; O'Neill, João Goyri; Branco, Jorge C.We designed and built a non-invasive instrument, called Vertebral Metrics, to measure the x, y, and z positions of each spinous process of the spine on a standing position. In the present study, we perform a comparative evaluation of Vertebral Metrics, by comparing the results obtained from this instrument with those from a validated optoelectronic system of stereophotogrammetry, with 10 infrared cameras. The s...