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Immune Checkpoint Inhibitor-Induced Thyroidal, Pancreatic, and Pituitary Dysfun...

Gil dos Santos, Sara; Calheiros, Raquel; Oliveira, Joana; Santos, Ana Paula; Inácio, Isabel

Immune checkpoint inhibitors (ICPIs)-induced endocrine immune-related adverse events (irAEs) are common, can appear concurrently, and can be overlooked due to their nonspecific presentation overlapping with cancer-related symptoms. We describe the case of a 47-year-old woman with metastatic colorectal cancer treated with combined ICPI therapy. She presented thyrotoxicosis right after starting therapy, evolving ...

Date: 2025   |   Origin: Acta Médica Portuguesa

Diagnosis and management of acromegaly: a consensus statement of the pituitary ...

Cardoso, Luís Miguel; Marques, Pedro; Pereira, Maria Teresa; Agapito, Ana; Almeida, Rui; Amaral, Sara; Cattoni, Maria Begona; Bugalho, Maria João

Acromegaly is characterised by hypersecretion of growth hormone and presents diagnostic and therapeutic challenges that require consensus and guidelines for effective management. The Pituitary Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism used a modified Delphi methodology to develop consensus recommendations for the diagnosis and management of acromegaly. A multidisciplinary p...


Transition to parenthood: Promotional strategies used by health professionals

Victória, Andrea; Costa, Catarina; Cordeiro, Marta; Santos, Ana Paula; Tavares, Márcio; Tavares, Patrícia

Background: The transition to parenthood is a multifactorial process directly influenced by multiple stakeholders. Objective: To identify and analyze healthcare professionals' strategies promoting the transition to parenthood. Methods: A scoping review was conducted following Joanna Briggs Institute guidelines. The research was carried out on the EBSCOhost platform for studies published between 2018 and 2023. E...


Factors influencing cessation of exclusive breastfeeding before six months of age

Carvalho, Sílvia; Rei, Patrícia; Moniz, Xénia; Santos, Ana Paula; Tavares, Márcio; Tavares, Patrícia

Background: Exclusive breastfeeding is crucial for infant health and development, but many factors can lead to its early cessation. Understanding these factors is essential for developing effective interventions. Objective: To identify and categorize the factors influencing the early cessation of exclusive breastfeeding before six months of age. Methods: This scoping review utilized the EbscoHost database aggre...


Needs of couples undergoing fertility treatment

Faria, Alexandra; Filipe, Filipa; Nogueira, Jesuina; Santos, Ana Paula; Tavares, Márcio

Background:  Infertility affects millions of couples, impacting 17.5% of the global population. Beyond being a medical condition, it affects multiple dimensions of life, including mental health, interpersonal relationships, and financial stability. Objective: To identify the needs experienced by couples diagnosed with infertility undergoing fertility treatment. Methods: A Scoping review was conducted following ...


Chronic Intestinal failure and short bowel syndrome in adults : the state of th...

Vara-Luiz, Francisco; Glória, Luísa; Mendes, Ivo; Carlos, Sandra; Guerra, Paula; Nunes, Gonçalo; Oliveira, Cátia Sofia; Ferreira, Andreia

Background: Short bowel syndrome (SBS) is a devastating malabsorptive condition and the most common cause of chronic intestinal failure (CIF). During the intestinal rehabilitation process, patients may need parenteral support for months or years, parenteral nutrition (PN), or hydration/electrolyte supplementation, as a bridge for the desired enteral autonomy. Summary: Several classification criteria have been h...


Home parenteral support in chronic intestinal failure : first results from a pi...

Mendes, Ivo; Vara-Luiz, Francisco; Palma, Carolina; Nunes, Gonçalo; Lima, Maria João; Oliveira, Cátia; Brito, Marta; Santos, Ana Paula

Background/Objectives: Home parenteral support (HPS) is the core of chronic intestinal failure (IF) treatment. For legal reasons, HPS in Portugal lags behind other European countries, and only a few patients were taken care of at home by nurses. Now, the legislation has changed, allowing patient self-care. The authors report their pioneer experience as the largest Portuguese IF center, evaluating the underlying...


The influence of pregnant’s body image on the decision to breastfeed: A systema...

Moniz Tavares, Márcio Filipe; Santos, Ana Paula; Silva, Sandra; Mendes, José

Objective: This systematic review aimed to assess scientific evidence regarding the association between body image and the decision to breastfeed during pregnancy. Methods: This study used the methodology proposed by the Joanna Briggs Institute and included studies from Scopus, Web of Science, B-On, and EBSCO. Inclusion criteria were primary studies published within the last 12 years, while gray literature, com...


The Influence of Pregnant’s Body Image on the Decision to Breastfeed: a systema...

Tavares, Márcio Moniz; Santos, Ana Paula; Silva, Sandra; Mendes, José

Objetivo: Esta revisão sistemática teve como objetivo avaliar as evidências científicas sobre a associação entre a imagem corporal e a decisão de amamentar ao longo da gravidez. Métodos: O estudo utilizou a metodologia proposta pelo Instituto Joanna Briggs, e incluiu estudos identificados nas bases de dados Scopus, Web of Science, B-On e EBSCO. Os critérios de inclusão foram estudos primários publicados nos últ...


Long-term intestinal failure and home parenteral support : a single center expe...

Brito, Mariana; Padinha, Mafalda; Carlos, Sandra; Oliveira, Cátia; Santos, Ana Paula; Nunes, Gonçalo; Santos, Carla Adriana; Fonseca, Jorge

Introduction: Home parenteral nutrition (HPN) and/or home parenteral hydration (HPH) are the gold-standard treatment for patients with long-term intestinal failure (IF). The authors aimed to assess the impact of HPN/HPH on nutritional status and survival of long-term IF patients, as well as HPN/HPH-related complications. Methods: This was a retrospective study including IF patients under HPN/HPH followed in a s...


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