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New Insights into pH-dependent Complex Formation between Lignosulfonates and An...

Pereira, AR; Bravo, C; Ramos, RM; Carina Costa; Rodrigues, A; de Freitas, V; Mateus, N; Dias, R; Soares, S; Joana Oliveira

Anthocyanins have limited application as natural colorants and antioxidants due to their color loss and instability under certain conditions. This research explores the formation of a complex between lignosulfonates (LS) and cyanidin-3-O-glucoside (C3G) using a multitechnique approach as well as the effect on C3G ' s red color, oxidative stability, and antioxidant activity in acidic mediums. All data revealed p...


First Insight into Lignin Valorization as a Promising Biopolymer for the Modula...

Pereira, AR; Brandao, E; Pinto, J; de Pinho, PG; Carina Costa; Rodrigues, AE; Michelin, M; Soares, S; de Freitas, V; Mateus, N; Oliveira, J

Lignosulfonate (LS), kraft lignin (KL), and organosolv lignin (OL) were evaluated as potential modulating agents of the physicochemical properties of Port wine at two different concentrations for 7 and 30 days. KL and LS demonstrated the ability to remove proteins and potentiate the anthocyanin concentration. LS reduced the tannin content and the interaction of salivary acidic proline-rich proteins with wine ph...


Disclosure of a promising lead to tackle complicated skin and skin structure in...

Gomes, A; Bessa, LJ; Fernandes, I; Ferraz, R; Monteiro, C; Martins, MCL; Mateus, N; Gameiro, P; Teixeira, C; Gomes, P

Efficient antibiotics are being exhausted, which compromises the treatment of infections, including complicated skin and skin structure infections (cSSTI) often associated with multidrug resistant (MDR) bacteria, methicillin-resistant S. aureus (MRSA) being the most prevalent. Antimi-crobial peptides (AMP) are being increasingly regarded as the new hope for the post-antibiotic era. Thus, future management of cS...


Anthocyanin content in raspberry and elderberry: The impact of cooking and reci...

Cordeiro, T; Iva Fernandes; Pinho, Olívia; Calha, C; Mateus, N; Faria, A

Background: Anthocyanins are known phytochemicals with beneficial properties for human health. The most important route of entry is by consumption of anthocyanins & rsquo; naturally rich food such as berries and red wine, in its natural form or as a part of recipes. The effect of cooking methods (boiling, steaming and baking) and recipe composition with two different berries, raspberry and elderberry, on the co...


Multiple-approach studies to assess anthocyanin bioavailability

Fernandes, I; Faria, A; de Freitas, V; Calhau, C; Mateus, N

Anthocyanins that are commonly ingested from the diet are largely conjugated, metabolized by colon microbiota and excreted in the urine and feces, yielding in a rather low bioavailability. Nevertheless, there are several health-promoting properties attributed to the ingestion of dietary anthocyanins including cardiovascular and neuroprotective effects, and the prevention of some types of cancer. There are many ...


The impact of chronic blackberry intake on the neuroinflammatory status of rats...

Meireles, M; Marques, C; Norberto, S; Fernandes, I; Mateus, N; Rendeiro, C; Spencer, JPE; Faria, A; Calhau, C

Neuroinflammation has been suggested as a central mediator of central nervous system dysfunction, including in dementia and neurodegenerative disease. Flavonoids have emerged as promising candidates for the prevention of neurodegenerative diseases and are thought to be capable of antiinflammatory effects in the brain. In the present study, the impact of a chronic intake of an anthocyanin extract from blackberry...


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