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Regulation of PKCβ levels and autophagy by PML is essential for high-glucose-de...

Morganti, Claudia; Missiroli, Sonia; Lebiedzinska-Arciszewska, Magdalena; Ferroni, Letizia; Morganti, Lucia; Perrone, Mariasole; Ramaccini, Daniela

Obesity is a complex disease characterized by the accumulation of excess body fat, which is caused by an increase in adipose cell size and number. The major source of adipocytes comes from mesenchymal stem cells (MSCs), although their roles in obesity remain unclear. An understanding of the mechanisms, regulation, and outcomes of adipogenesis is crucial for the development of new treatments for obesity-related ...


Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSE...

Sartelli, Massimo; Abu-Zidan, Fikri M.; Labricciosa, Francesco M.; Kluger, Yoram; Coccolini, Federico; Ansaloni, Luca; Leppäniemi, Ari

Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. The objectives of this study were to identify clinical and laboratory predictors for in-hospital mortality in patients with acute peri...


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