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The CgHaa1-regulon mediates response and tolerance to acetic acid stress in the...

Bernardo, Ruben T.; Cunha, Diana V.; Wang, Can; Pereira, L. P.; Silva, Sónia Carina; Salazar, Sara B.; Schröder, Markus S.; Okamoto, Michiyo

To thrive in the acidic vaginal tract C. glabrata has to cope with high concentrations of acetic acid. The mechanisms underlying C. glabrata tolerance to acetic acid at low pH remain largely uncharacterized. In this work it is demonstrated the essential role of the CgHaa1 transcription factor (encoded by ORF CAGL0L09339g) in the response and tolerance of C. glabrata to acetic acid. Transcriptomic analysis showe...


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