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Bioactive compounds in the leaves of Baccharis dracunculifolia: extraction proc...

Iurckevicz, Genice; Dahmer, Débora; Casagrande, Maira; Calegari, Gabrielle Cristina; Oldoni, Tatiane Luiza Cadorin; Dekker, Robert Frans Huibert

Baccharis dracunculifolia has been used in popular medicine because of its bioactive properties, which include anti-inflammatory, antiulcerative and hepatoprotective potentials. A 2³ central composite rotational design was used to define the best conditions for extracting the bioactive compounds from the leaves of Baccharis dracunculifolia. The parameters studied included the solvent concentration, time and tem...

Date: 2021   |   Origin: Oasisbr


Bioactive compounds from Syzygium malaccense leaves: optimization of the extrac...

Savi, Aline; Calegari, Matheus Augusto; Calegari, Gabrielle Cristina; Santos, Vidiany Aparecida Queiroz; Wermuth, Denise; Cunha, Mário Antônio Alves da

Syzygium malaccense belongs to the family Myrtaceae and it is popularly recognised as ‘jambo’ in Brazil. It is poorly studied regarding the bioactive compounds of fruits and leaves. This study aimed at optimizing the extraction and characterization of bioactives compounds from S. malaccense leaves. Extraction was optimized using a 23 full factorial design to evaluate the effect of ethanol concentration, time an...

Date: 2020   |   Origin: Oasisbr

Bioassay - guided isolation of proanthocyanidins with antioxidant activity from...

Oldoni, Tatiane Luiza Cadorin; Melo, Priscilla Siqueira; Massarioli, Adna Prado; Moreno, Ivani Aparecida Marchetto; Bezerra, Rosangela Maria Neves

Purification and bioassay-guided fractionation were employed to isolate proanthocyanidins with antioxidant activity from peanut skin (Arachis hypogaea Runner 886). The crude extract was prepared with acetone (60% v/v) and purified using chromatographic methods, including a semipreparative HPLC technique. As a result, two proanthocyanidins were isolated and identified using NMR, epicatechin-(2 b?O?7, 4 b?8)-cate...

Date: 2016   |   Origin: Oasisbr

The correlation between the phenolic composition and biological activities of t...

Cabral, Ingridy Simone Ribeiro; Oldoni, Tatiane Luiza Cadorin; Alencar, Severino Matias de; Rosalen, Pedro Luiz; Ikegaki, Masaharu

Biological assays that have been performed on different types of Brazilian propolis have shown that type 6 propolis (G6) has a strong antimicrobial activity and a low flavonoid content. This study aimed to evaluate the correlation between the phenolic composition and the biological activities displayed by propolis G6 from the state of Bahia and green propolis, also known as type 12 (G12). The values of the flav...

Date: 2012   |   Origin: Oasisbr

Isolation and analysis of bioactive isoflavonoids and chalcone from a new type ...

Oldoni, Tatiane Luiza Cadorin; Cabral, Ingridy Simone Ribeiro; d’Arce, Marisa Aparecida Bismara Regitano; Rosalen, Pedro Luiz; Ikegaki, Masaharu

Activity-directed fractionation and purification processes were employed to identify isoflavonoids with antioxidant and antimicrobial activities from Brazilian red propolis. Crude propolis was extracted with ethanol (80%, v/v) and fractioned by liquid–liquid extraction technique using hexane and chloroform. Since chloroform fraction showed strong antioxidant and antimicrobial activities it was purified and isol...

Date: 2012   |   Origin: Oasisbr

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