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Hemotropic Mycoplasma and Bartonella Species Diversity in Free-Roaming Canine a...

Mesquita, JR; Oliveira, AC; Neves, F; Mendoza, JR; Luz, MF; Crespo, I; Dos Santos, TF; Santos-Silva, S; Vilhena, H; Barradas, PF

Free-roaming dogs and cats represent potential reservoirs for zoonotic vector-borne pathogens shedding to the human population. Given the health impact of these pathogens, we searched free-roaming dogs and cats included in an animal population control program from Luanda, Angola, for Bartonella and hemotropic mycoplasma infection. We report the detection of Bartonella henselae (2/66; 3%), Candidatus Mycoplasma ...


Poly-resistant tuberculosis outbreak in Northern Portugal: a nine year tale

Gomes, B; Molina-Correa, G; Neves-Reina, L; Oliveira, AC; Macedo, R; Carvalho, C; Correia, AM

In 2017, the notification rate of tuberculosis in the Northern Region of Portugal was 21.1 cases per 100 000 inhabitants. According to the National Tuberculosis Programme Surveillance System (SVIG-TB), poly-resistance to isoniazid and streptomycin (PR-HS) represented 2.6–5% of the cases notified in the Northern Region between 2009 and 2017 Although they represent a relatively low proportion of cases in Portugal...


Serological and molecular evidence of Bartonella henselae in cats from Luanda c...

Barradas, PF; de Sousa, R; Vilhena, H; Oliveira, AC; Luz, MF; Granada, S; Cardoso, L; Lopes, AP; Gonçalves, H; Mesquita, JR; Ferreira, P; Amorim, I

A total of 100 domestic cats from Luanda (Angola) were tested for the presence of antibodies against Bartonella henselae and spotted fever group of Rickettsia (SFGR) using indirect immunofluorescence assay (IFA). Molecular screening targeting the riboflavin synthase (ribC) gene for Bartonella and outer membrane protein B (ompB) gene for Rickettsia, using conventional PCR and sequencing was also performed in cat...


Combined study of ADAMTS13 and complement genes in the diagnosis of thrombotic ...

Fidalgo, T; Martinho, P; Pinto, CS; Oliveira, AC; Salvado, R; Borràs, N; Coucelo, M; Manco, L; Maia, T; Mendes, MJ; Del Orbe Barreto, R; Corrales, I

BACKGROUND: The 2 main forms of thrombotic microangiopathy (TMA) are thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS). Deficiency of ADAMTS13 and dysregulation of the complement pathway result in TTP and aHUS, respectively; however, overlap of their clinical characteristics makes differential diagnosis challenging. OBJECTIVES AND METHODS: We aimed to develop a TMA diagnosi...


Potassium urinary excretion and dietary intake: a cross-sectional analysis in 8...

Oliveira, AC; Padrão, Patrícia; Moreira, A; Pinto, M; Neto, M; Santos, T; Madureira, J; Fernandes, ED; Graça, Pedro; Breda, J; Moreira, Pedro

[Erratum]


Familial thrombotic risk based on the genetic background of Protein C Deficienc...

Fidalgo, T; Martinho, P; Salvado, R; Manco, L; Oliveira, AC; Pinto, CS; Gonçalves, E; Marques, D; Sevivas, T; Martins, N; Ribeiro, ML

INTRODUCTION: Inherited protein C (PC) deficiency is a well-known risk factor for venous thrombosis (VT). Plasma PC levels are reliable in moderate to severe deficiencies; however, in mildly deficient individuals, the levels may overlap with those considered normal. Genetic studies of PROC, which encodes PC, could help identify carriers; genome-wide association studies (GWAS) have shown that approximately 50% o...


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