.
A psoríase pustular generalizada (PPG), ou de Von Zumbush, é uma variante rara e potencialmente fatal da psoríase. Caracteriza-se por um exantema generalizado com múltiplas lesões pustulosas, estéreis, que levam a descolamento cutâneo. Os fatores desencadeantes mais frequentes incluem infeções, alterações eletrolíticas e fármacos, inclusive o desmame inadequado de corticoterapia. O diagnóstico definitivo é hist...
Background: The antioxidant potential of craft beer (CB) may be due to high quality of the raw materials (water, malt, hop and yeast) and traditional techniques [1-4]. The scarcity of studies evaluating the antioxidant potential of CB highlights the relevance of this study. Objective: In vitro evaluation of the antioxidant activity of aqueous extracts of Portuguese and Spanish CB. Methods: Experimental study us...
Background: The materials in which beverages are packed are crucial to maintain quality, nutritional properties, and safety of the final product. In what beer concerns, and even under optimal storage conditions, its quality deteriorates as the product approaches the expiration date, regardless of the container type in which it is packed [1]. Therefore, a careful selection of packaging is imperative to maintain ...
The materials in which beverages are packed are crucial to maintain quality, nutritional properties, and safety of the final product. In what beer concerns, and even under optimal storage conditions, its quality deteriorates as the product approaches the expiration date, regardless of the container type in which it is packed. Therefore, a careful selection of packaging is imperative to maintain beer ́s integrit...
Polypharmacy in older adults with cancer receiving chemotherapy leads to increased risks of drug interactions, translating in potential hazardous health outcomes. This study aims to assess the prevalence of polypharmacy, drug–drug interactions (DDIs), and severe-drug interactions (SDIs) in older patients with cancer. Antineoplastic agents (ANAs) involvement and possible risk contexts (comorbidities with cardiac...
The antioxidant potential of craft beer (CB) may be due to high quality of the raw materials (water, malt, hop and yeast) and traditional techniques. The scarcity of studies evaluating the antioxidant potential of CB highlights the relevance of thisstudy. In vitroevaluation of the antioxidant activity of aqueous extracts of Portuguese and Spanish CB. Experimental study using six CB with different styles: Milk S...
The complexity of antineoplastic preparation increases the risk of errors, thus demanding robust safety systems. Common methods to prevent errors committed during aseptic preparation include double visual verification and gravimetric control (GC), in which the mass of each preparation is determined to ensure product accuracy. The aim of this work is to develop a GC that routinely, quickly, and simply enables qu...
Selective COX-2 inhibitors such as etoricoxib (ETX) are potentially indicated for the treatment of intestinal inflammatory disorders. However, their systemic administration provokes some off-site secondary effects, decreasing the desirable local effectiveness. To circumvent such limitations, herein an ETX delivery system based on electrospun fibrous meshes (eFMs) was proposed. ETX at different concentrations (1...