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Melanoma: Uma Localização Rara

Oliveira, Ana Isabel; Quaresma, Marta; Cruz, Sofia; Ferreira, Bruno

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Date: 2024   |   Origin: SPMI Case Reports

Generalized Pustular Psoriasis: A Case Report

Abreu, Jéssica; Oliveira, Ana Isabel; Cruz, Sofia; Nunes, Gilda; Maio, Paula

A psoríase pustular generalizada (PPG), ou de Von Zumbush, é uma variante rara e potencialmente fatal da psoríase. Caracteriza-se por um exantema generalizado com múltiplas lesões pustulosas, estéreis, que levam a descolamento cutâneo. Os fatores desencadeantes mais frequentes incluem infeções, alterações eletrolíticas e fármacos, inclusive o desmame inadequado de corticoterapia. O diagnóstico definitivo é hist...

Date: 2024   |   Origin: SPMI Case Reports

A Rare Triad: Plummer Vinson Syndrome

Oliveira, Ana Isabel; Gomes, Carolina; Ferreira, Bruno; Abuowda, Yahia

Date: 2024   |   Origin: SPMI Case Reports

Antioxidant profile of Portuguese and Spanish craft beers

Pereira, Maria João; Santos, Diana; Pinho, Cláudia; Oliveira, Ana Isabel

Background: The antioxidant potential of craft beer (CB) may be due to high quality of the raw materials (water, malt, hop and yeast) and traditional techniques [1-4]. The scarcity of studies evaluating the antioxidant potential of CB highlights the relevance of this study. Objective: In vitro evaluation of the antioxidant activity of aqueous extracts of Portuguese and Spanish CB. Methods: Experimental study us...

Date: 2024   |   Origin: Scientific Letters

Potential impact of packaging type material in beer quality

Santos, Diana; Pereira, Maria João; Oliveira, Ana Isabel; Pinho, Cláudia

Background: The materials in which beverages are packed are crucial to maintain quality, nutritional properties, and safety of the final product. In what beer concerns, and even under optimal storage conditions, its quality deteriorates as the product approaches the expiration date, regardless of the container type in which it is packed [1]. Therefore, a careful selection of packaging is imperative to maintain ...

Date: 2024   |   Origin: Scientific Letters

Potential impact of packaging type material in beer quality

Santos, Diana; Pereira, Maria João; Oliveira, Ana Isabel; Pinho, Cláudia

The materials in which beverages are packed are crucial to maintain quality, nutritional properties, and safety of the final product. In what beer concerns, and even under optimal storage conditions, its quality deteriorates as the product approaches the expiration date, regardless of the container type in which it is packed. Therefore, a careful selection of packaging is imperative to maintain beer ́s integrit...


Polypharmacy and drug interactions in older patients with cancer receiving chem...

Ferraz Oliveira, Rita; Oliveira, Ana Isabel; Cruz, Agostinho; Ribeiro, Oscar; Afreixo, Vera; Pimentel, Francisco

Polypharmacy in older adults with cancer receiving chemotherapy leads to increased risks of drug interactions, translating in potential hazardous health outcomes. This study aims to assess the prevalence of polypharmacy, drug–drug interactions (DDIs), and severe-drug interactions (SDIs) in older patients with cancer. Antineoplastic agents (ANAs) involvement and possible risk contexts (comorbidities with cardiac...


Antioxidant profile of Portuguese and Spanish craft beers

Pereira, Maria João; Santos, Diana; Oliveira, Ana Isabel; Pinho, Cláudia

The antioxidant potential of craft beer (CB) may be due to high quality of the raw materials (water, malt, hop and yeast) and traditional techniques. The scarcity of studies evaluating the antioxidant potential of CB highlights the relevance of thisstudy. In vitroevaluation of the antioxidant activity of aqueous extracts of Portuguese and Spanish CB. Experimental study using six CB with different styles: Milk S...


Development and implementation of a gravimetric control method for chemotherape...

Fonseca, Débora; Ré, Susana; Cruz, José Pedro; Oliveira, Ana Isabel; Moreira, Fernando; Moreira, Fernando; Oliveira, Ana Isabel

The complexity of antineoplastic preparation increases the risk of errors, thus demanding robust safety systems. Common methods to prevent errors committed during aseptic preparation include double visual verification and gravimetric control (GC), in which the mass of each preparation is determined to ensure product accuracy. The aim of this work is to develop a GC that routinely, quickly, and simply enables qu...


COX-2 inhibitor delivery system aiming intestinal inflammatory disorders

Oliveira, Ana Isabel; Rodrigues, Luísa Cidália Guimarães; Soares da Costa, Diana; Fernandes, E. M.; Reis, R. L.; Neves, N. M.; Leão, P.; Martins, Albino

Selective COX-2 inhibitors such as etoricoxib (ETX) are potentially indicated for the treatment of intestinal inflammatory disorders. However, their systemic administration provokes some off-site secondary effects, decreasing the desirable local effectiveness. To circumvent such limitations, herein an ETX delivery system based on electrospun fibrous meshes (eFMs) was proposed. ETX at different concentrations (1...


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