9 documents found, page 1 of 1
Reproductive toxicity assessment of four portuguese plant hydrolates: Effects o...
Dias, Sandra D.F.; Andrade, L.P.; Rolo, Joana; Gaspar, Carlos; Ruivo, Patrícia Gomes; Oliveira, Ana Sofia; Ferreira, Sandra SaraivaExtracts of aromatic medicinal plants have been extensively studied regarding their numerous bioactivities. However, despite being highly used by humans, studies on the safety of these extracts for animal use are scarce. In this study, we aim to contribute to the determination of the safety profile of plant extracts by focusing on the reproductive toxicity of hydrolates (a by-product of essential oils productio...
Humulus lupulus aqueous extract and hydrolate as a potential ingredient for cos...
Valente, João Vasco; Oliveira, Rita Palmeira de; Guiomar, Liliana; Vaz, Cátia; Rolo, Joana; Gaspar, Carlos; Oliveira, Ana Sofia; Caramelo, DéboraHumulus lupulus extracts have in their composition different molecules, such aspolyphenols, α-acids, β -acids, and hydrocarbons, which contribute to the plant’s medicinal properties. These molecules are associated with antimicrobial, antioxidant, and anti - inflammatory activities. OBJECTIVE This work focuses on the evaluation of H. lupulus biological activities, with the aim of evaluating its potential for inc...
Effect of plant extracts in sperm viability
Dias, Sandra D.F.; Andrade, L.P.; Rolo, Joana; Delgado, F.M.G.; Oliveira, Ana Palmeira de; Gaspar, Carlos; Ruivo, Patrícia GomesMedicinal plants have been used since the earliest documented history around the world, as an available and inexpensive therapeutic resource. Plant based bioactive elements play eminent biological roles as antioxidant, anti-inflammatory and antiproliferative agents. It is proved that naturally occurring antioxidants in ethnomedicinal plants are effective in treating various types of diseases. However, herbal me...
Chemical profile and eco-safety evaluation of essential oils and hydrolates fro...
Ferraz, Celso Afonso; Sousa, Ana Catarina A.; Oliveira, Ana Palmeira de; Pastorinho, M. Ramiro; Caramelo, Débora; Delgado, F.M.G.The demand for natural-based products for industrial applications is increasing sharply and therefore the search for new alternatives to the plants traditionally used is growing. These alternative plants can be an important source of bioactive compounds under a circular economy approach. Considering the potential future use of new plant extracts by the industry, it is necessary to assess the risk associated wit...
Regulamentação dos produtos cosméticos: uma perspetiva da evolução em Portugal ...
Ferreira, Marta S.; Oliveira, Ana Palmeira de; Oliveira, Rita; Oliveira, Rita Palmeira de; Lobo, José M. Sousa; Almeida, IsabelOs produtos cosméticos são produtos de saúde destinados a contactar com as partes externas do corpo humano, dentes e mucosas bucais, tendo em vista, exclusiva ou principalmente, limpá-los, perfumá-los, modificar-lhes o aspeto, protegê-los, mantê-los em bom estado ou corrigir os odores corporais. A sua regulamentação na atual União Europeia (UE) começou por ser realizada a nível nacional, materializando-se em Po...
Chemical signature and antimicrobial activity of Central Portuguese Natural Min...
Oliveira, AS; Vaz, CV; Silva, Ana; Ferreira, Sandra S.; Correia, Sara; Ferreira, Raquel; Granadeiro, Luiza Breitenfeld; Oliveira, J. Martinez deThe common therapeutic indications of Portuguese Natural Mineral Waters (NMWs) are primarily for respiratory, rheumatic and muscu- loskeletal systems. However, these NMWs have been increasingly sought for dermatologic purposes. Opposing to what is observed in the major European Thermal Centres, there are few scientific evidences supporting the use of Portuguese NMWs for clinical applications. The aim of this st...
Bacteriocin production of the probiotic Lactobacillus acidophilus KS400
Gaspar, C; Donders, Gilbert; Oliveira, Rita Palmeira de; Queiroz, João; Tomaz, C. T.; Oliveira, J. Martinez de; Oliveira, Ana Palmeira deIn the last years, the use of probiotics, including Lactobacillus species, has received much attention to prevent and treat vaginal disorders. These species have been described as having the ability to colonize the epithelial surface and produce antimicrobial metabolites that are able to control the remaining vaginal microflora. This study aimed to identify and characterize, for the first time, a bacteriocin na...
Bacterial vaginosis biofilms: challenges to current therapies and emerging solu...
Machado, D.; Castro, J.; Oliveira, Ana Palmeira de; Oliveira, José Martinez de; Cerca, NunoBacterial vaginosis (BV) is the most common genital tract infection in women during their reproductive years and it has been associated with serious health complications, such as preterm delivery and acquisition or transmission of several sexually transmitted agents. BV is characterized by a reduction of beneficial lactobacilli and a significant increase in number of anaerobic bacteria, including Gardnerella va...
Anti-Candida activity of a chitosan hydrogel: mechanism of action and cytotoxic...
Oliveira, Ana Palmeira de; Ribeiro, MP.; Oliveira, Rita Manuela Palmeira de; Gaspar, Carlos; Oliveira, Sofia Costa de; Correia, I.J.; Vaz, Cidália PinaCandida spp. are common causative agents of mucocutaneous infections. New therapeutic antifungal drugs are needed to treat chronic disease as these are frequently clinically resistant to azols. Chitosan, among other possible vehicles for active compounds, shows an added value as it appears to have intrinsic antimicrobial properties. The aim of the present study was to evaluate the anti-Candida activity of a med...