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Valorisation of protein-rich extracts from spent brewer’s yeast (Saccharomyces ...

Oliveira, Ana Sofia; Ferreira, Carlos; Pereira, Joana Odila; Pintado, Manuela E.; Carvalho, Ana P.

As one of the main brewing by-products, Saccharomyces cerevisiae extracts (from spent yeast) have been commercialized as food supplement for years. Among their several claims, the application as protein source is highlighted. In fact, their high protein content (about 45–60%) including essential amino acids with high biological value, safety and low cost are primarily responsible for their spreading in agri-foo...


Reproductive toxicity assessment of four portuguese plant hydrolates: Effects o...

Dias, Sandra D.F.; Andrade, L.P.; Rolo, Joana; Gaspar, Carlos; Ruivo, Patrícia Gomes; Oliveira, Ana Sofia; Ferreira, Sandra Saraiva

Extracts of aromatic medicinal plants have been extensively studied regarding their numerous bioactivities. However, despite being highly used by humans, studies on the safety of these extracts for animal use are scarce. In this study, we aim to contribute to the determination of the safety profile of plant extracts by focusing on the reproductive toxicity of hydrolates (a by-product of essential oils productio...


Unlocking Nature’s Anti-Aging Secrets: The Potential of Natural Mineral Waters ...

Gama, Ana Rita; Gomes, Carolina P.; Caetano, Cátia; Oliveira, Ana Sofia; Rolo, Joana; Barros, Lillian; Plasencia, Paula; Garcia, Juliana

Skin aging is influenced by intrinsic and extrinsic factors, leading to structural changes in the skin. Current anti-aging cosmetic trends emphasize innovative natural ingredients, including plant extracts, thermal waters, and botanical hydrolats. This work aims to develop six natural anti-aging cosmetics (two serums, two day creams, and two night creams) with innovative and non-irritating profiles. The rationa...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Sex differences in health-related quality of life among individuals at high ris...

Oliveira, Ana Sofia; Lopes, Sílvia; Ferreira, Lara; Cruz, Vítor Tedim; Costa, Ana Rute

Purpose Dementia represents an increasing challenge to health systems globally, with a notable impact on health-related quality of life (HRQoL). Nevertheless, the potential effect of sex on the relation between individuals’ characteristics and HRQoL, particularly in the early stages of this disease, remains unclear. Therefore, the present study aims to evaluate the association between sociodemographic, lifestyl...



Purification of bioactive peptides from spent yeast autolysates

Oliveira, Ana Sofia; Pereira, Ana Margarida; Ferreira, Carlos M.H.; Pereira, Joana Odila; Amorim, Manuela; Faustino, Margarida; Durão, Joana

Spent brewer’s yeast have been described as an important source for bioactive peptides, with their properties well proven over the years. Besides the brewing sector, growing of large-scale processes on synthetic biology industry has generated a substantial amount of spent engineered yeast with further potential to be valued in a circular economy approach. In line with this perception, in this work, peptide-rich...


Up-scalable approaches for yeast mannan oligosaccharides (MOS) production: char...

Faustino, Margarida; Durão, Joana; Pereira, Carla F.; Pereira, Ana Margarida; Oliveira, Ana Sofia; Sousa, Sérgio; Ribeiro, Alessandra Braga

Mannan oligosaccharides (MOS) are widely used as feed additives due to their effects on gut microbiome modulation. Its application in the nutraceutical and functional food industries is also increasing. Numerous studies portraying MOS production from β-mannans can be found, but its production from yeast mannans is barely explored. Herein, two up-scalable approaches to produce yeast-derived MOS are presented: hy...


Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and ...

Faustino, Margarida; Pereira, Joana Odila; Pereira, Ana Margarida; Oliveira, Ana Sofia; Ferreira, Carlos M. H.; Pereira, Carla F.; Durão, Joana

Vulvovaginal candidiasis (VVC) affects approximately 30-50% of women at least once during their lifetime, causing uncomfortable symptoms and limitations in their daily quality of life. Antifungal therapy is not very effective, does not prevent recurrencies and usually causes side effects. Therefore, alternative therapies are urgently needed. The goal of this work was to investigate the potential benefits of usi...


Use of various sugarcane byproducts to produce lipid extracts with bioactive pr...

Pereira, Joana Odila; Oliveira, Diana; Faustino, Margarida; Vidigal, Susana S. M. P.; Pereira, Ana Margarida; Ferreira, Carlos M. H.

Sugarcane, a globally cultivated crop constituting nearly 80% of total sugar production, yields residues from harvesting and sugar production known for their renewable bioactive compounds with health-promoting properties. Despite previous studies, the intricate interplay of extracts from diverse sugarcane byproducts and their biological attributes remains underexplored. This study focused on extracting the lipi...


An eco-friendly and up-scalable approach to extract canthaxanthin from yeast cells

Pereira, Ana M.; Durão, Joana; Pereira, Joana Odila; Ferreira, Carlos; Faustino, Margarida; Oliveira, Ana Sofia; Pereira, Carla F.; Pintado, Manuela E.

Canthaxanthin is a naturally occurring ketocarotenoid pigment present in plants, algae, bacteria and some fungi. In addition to its coloring role, canthaxanthin has an excellent antioxidant activity, thus having additional market demands in the feed, food, cosmetic and pharmaceutical industries. Canthaxanthin can be directly isolated from its natural source or produced by chemical synthesis, but these strategie...


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