3 documents found, page 1 of 1
Effects of Non-Conventional Sterilisation Methods on PBO-Reinforced PVA Hydroge...
Pires, Tomás; Oliveira, Andreia Sofia; Marques, Ana Clara; Salema-Oom, Madalena; Figueiredo-Pina, Célio; Silva, Diana; Serro, Ana PaulaArticular cartilage (AC) degradation is a recurrent pathology that affects millions of people worldwide. Polyvinyl alcohol (PVA) hydrogels have been widely explored for AC replacement. How- ever, their mechanical performance is generally inadequate, and these materials need to be reinforced. Moreover, to be used in a clinical setting, such materials must undergo effective sterilisation. In this work, a PVA hydr...
Effects of non-conventional sterilisation methods on PBO-reinforced PVA hydroge...
Pires, Tomás; Oliveira, Andreia Sofia; Marques, Ana Clara; Salema-Oom, Madalena; Figueiredo-Pina, Célio G.; Silva, Diana; Serro, Ana PaulaArticular cartilage (AC) degradation is a recurrent pathology that affects millions of people worldwide. Polyvinyl alcohol (PVA) hydrogels have been widely explored for AC replacement. However, their mechanical performance is generally inadequate, and these materials need to be reinforced. Moreover, to be used in a clinical setting, such materials must undergo effective sterilisation. In this work, a PVA hydrog...
Tough and low friction polyvinyl alcohol hydrogels loaded with anti-inflammator...
Oliveira, Andreia Sofia; Schweizer, Sara; Nolasco, Pedro; Barahona, Isabel; Saraiva, Jorge; Colaço, Rogério; Serro, Ana PaulaThe development of new materials that mimic cartilage and its function is an unmet need that will allow replacing the damaged parts of the joints, instead of the whole joint. Polyvinyl alcohol (PVA) hydrogels have raised special interest for this application due to their biocompatibility, high swelling capacity and chemical stability. In this work, the effect of post-processing treatments (annealing, high hydro...